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抑制剂&激动剂
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  • 抑制剂&激动剂
    13
    TargetMol | Inhibitors_Agonists
  • 天然产物
    2
    TargetMol | Natural_Products
  • Blarcamesine
    AE-37, AVex-73
    T7780195615-83-9
    Blarcamesine (AVex-73) 是一种毒蕈碱 M1 激动剂,具有抗惊厥、抗失忆、神经保护和抗抑郁的特性,可能用于治疗阿尔茨海默病。
    • ¥ 266
    In stock
    规格
    数量
  • Prolyl Endopeptidase Inhibitor 1
    (Boc)-Prolyl-prolinal,BPP,Boc-Pro-prolinal
    T1254686925-97-5In house
    Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP; PE)(Ki : 15 nM) , has anti-amnesic effect.
    • ¥ 1820
    5日内发货
    规格
    数量
  • KW-6055
    T1179163233-46-5
    KW-6055 has anti-amnesic activity, is a benzylpyridine derivative.
    • ¥ 10600
    6-8周
    规格
    数量
  • Salicortin
    特里杨甙
    T128281887055-63-1
    Salicortin is a phenolic glycoside isolated from many plants such as Populus and Salix species, has anti-adipogenic, anti-amnesic, and immune-modulatory activity.
    • 待询
    3-6月
    规格
    数量
  • ONO-2952
    T16393895169-20-7
    ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. ONO-2952 is a potent and selective translocator protein 18 kDa (TSPO) antagonist (Ki: 0.33-9.30 nM for rat and human TSPO). ONO-2952 has the potential for i
    • ¥ 11700
    6-8周
    规格
    数量
  • Longestin
    KS-505a
    T200079131774-53-3
    Longestin,源自Streptomyces argenteolus,是一种磷酸二酯酶 (phosphodiesterase) 抑制剂,具备抗锥虫活性,有望应用于抗遗忘药物的开发研究中。
    • 待询
    规格
    数量
  • DBO-83
    DBO83
    T20912195211-53-1
    DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.
    • 待估
    35日内发货
    规格
    数量
  • DBO-83 free base
    DBO 83 free base
    T31220286946-32-5
    DBO-83 free base 是 DBO-83的游离碱形式。游离碱 DBO-83是烟碱型乙酰胆碱受体(nAChRs)的激动剂,具有抗遗忘和抗伤害的活性。
    • ¥ 10600
    待询
    规格
    数量
  • (+/-)-PPCC oxalate
    T37013932736-91-9
    Selective sigma (σ) receptor ligand. Displays high affinity for σ1; also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Selective over a range of receptor types including dopaminergic and muscarinic receptors, DAT and SERT. Prezzavento et al (2007) Novel sigma receptor ligands: synthesis and biological profile. J.Med.Chem. 50 951 PMID:17328523 |Prezzavento et al (2008) A new sigma ligand, (±)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect. Life Sci. 82 549 PMID:18261749 |Antonini et al (2009) Anti-amnesic properties of (±)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J.Neurochem. 109 744 PMID:19245662
    • ¥ 10600
    6-8周
    规格
    数量
  • Fluoroethylnormemantine hydrochloride
    T391191639210-25-5
    Fluoroethylnormemantine hydrochloride, a Memantine derivative, functions as an antagonist for the N-methyl-D-aspartate (NMDA) receptor. It can also serve as a positron emission tomography (PET) tracer, specifically as [18F]-Fluoroethylnormemantine hydrochloride. Notably, this compound displays a range of effects, including anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties.
    • ¥ 2990
    5日内发货
    规格
    数量
  • Fluoroethylnormemantine
    T391201639210-26-6
    Fluoroethylnormemantine, a derivative of Memantine, acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. It can function as a positron emission tomography (PET) tracer, known as [18F]-fluoroethylnormemantine. This compound displays anti-amnesic, neuroprotective, antidepressant-like, and fear-attenuating properties.
    • 待询
    5日内发货
    规格
    数量
  • Decursin
    Decursinol angelate, 前胡素, (+)-Decursin
    T3S14165928-25-6
    Decursin (Decursinol angelate) 是一种细胞毒性剂,是一种来自朝鲜当归根的有效蛋白激酶 C 激活剂。它通过 Hippo YAP 信号通路抑制 HepG2 细胞的生长。它通过下调 CXCR7 表达来抑制胃癌中的肿瘤生长,迁移和侵袭。
    • ¥ 298
    In stock
    规格
    数量
    TargetMol | Inhibitor Sale
  • Acanthoside B
    无梗五加苷B, 无梗五加苷 B, 刺五加提取物
    TN13557374-79-0
    Acanthoside B 是一种具有抗炎和抗遗忘作用的木脂素。 Acanthoside B 可用于关于阿尔茨海默病和肺部炎症的研究。
    • ¥ 542
    In stock
    规格
    数量
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