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Search Results for "VZ185"
Targets Recommended: Epigenetic Reader Domain

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Cat. No. Product Name Target Signaling Pathways
T17697 BRD7-IN-1

Epigenetic Reader Domain Chromatin/Epigenetic
BRD7-IN-1 是一种修饰的 BI7273 衍生物 (BRD7/9 抑制剂)。BRD7-IN-1 通过与 VHL 配体连接形成PROTAC VZ185VZ185 抑制 BRD7/9 的 DC50分别是 4.5 nM和1.8 nM。
T17696 BRD7-IN-1 free base

Others Others
BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively)[1].
T17249 VZ185

Epigenetic Reader Domain Chromatin/Epigenetic
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).

化合物

BRD7-IN-1
T17697
synonym:
Target: Epigenetic Reader Domain
BRD7-IN-1 free base
T17696
synonym:
Target: Others
VZ185
T17249
synonym:
Target: Epigenetic Reader Domain