| Cat. No. | Product Name | Target | Signaling Pathways |
|---|---|---|---|
| T17697 | BRD7-IN-1 | Epigenetic Reader Domain | Chromatin/Epigenetic |
| BRD7-IN-1 是一种修饰的 BI7273 衍生物 (BRD7/9 抑制剂)。BRD7-IN-1 通过与 VHL 配体连接形成PROTAC VZ185。VZ185 抑制 BRD7/9 的 DC50分别是 4.5 nM和1.8 nM。 | |||
| T17696 | BRD7-IN-1 free base | Others | Others |
| BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively)[1]. | |||
| T17249 | VZ185 | Epigenetic Reader Domain | Chromatin/Epigenetic |
| VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively). | |||
沪公网安备 31010602006700号
