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Search Results for " l-histidine "

Targets Recommended: Others

20

抑制剂 & 化合物

6

天然产物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40122	L-Histidine benzyl ester bistosylate	Others	Others
	L-Histidine benzyl ester bistosylate may serve as an activator for HutP, an RNA-binding protein.
T3937	Methyl L-histidinate dihydrochloride L-Histidine methyl ester dihydrochloride,L-组氨酸甲酯二盐酸盐	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) 在Sprague-Dawley 大鼠胃中组氨酸脱羧酶的抑制作用被评估为 14CO2 产生减少，活性值为 1.8 μM。
T32735	L-Histidine S-malate
	L-Histidine S-malate is a bioactive chemical.
T81677	N-Formyl-L-histidine Formyl-L-histidine
	N-Formyl-L-histidine 通过与组氨酸-tRNA合成酶结合展示其活性，其Ki值为4.6 μM。此外，N-Formyl-L-histidine作为L-组氨酸解氨酶的竞争性抑制剂，具有4.26 mM的Ki值，能够有效抑制该酶对L-组氨酸的解氨反应，阻止尿苷酸的生成。
T33702	N-Mercaptoacetyl-L-histidine SA 120,L-Histidine, N-(mercaptoacetyl)-,SA120,SA-120
	N-Mercaptoacetyl-L-histidine is a peptide.
T66645	Fmoc-His-OH (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid,(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine,FMOC-L-Histidine
	(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid 是一种组氨酸衍生物。
TP1088	N-Acetylcarnosine N-Acetyl-L-carnosine,N-乙酰肌肽	Others	Others
	N-Acetylcarnosine (N-Acetyl-L-carnosine) 是一种含有组氨酸的天然二肽，是药理学上主要的 L-carnosine 的来源。它是一种眼科药物，对人类白内障具有潜在的应用价值。
T33760	N-Stearoylhistidine N-Stearoyl-L-histidine
	N-Stearoylhistidine is a bioactive chemical.
T24974	2-Iodohistidine 2-Iodo-L-histidine
	2-Iodohistidine shows potent antimalarial activity.
T20382	Diglycyl-histidine NSC334195,NSC-334195,Gly-gly-his,Glycylglycyl-L-histidine,NSC 334195
	Diglycyl-histidine is a tripeptide complexed with cupric ion designed to mimic specific Cu(II) transport site of ascorbate on albumin molecule.
T65767	N-Cbz-L-histidine
	N-Cbz-L-histidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T65767。
T66680	Fmoc-1-methyl-L-histidine
	Fmoc-1-methyl-L-histidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66680，CAS号为 202920-22-7。
T9372	D-Histidine	Mitochondrial Metabolism	Metabolism
	D-Histidine 是一种 L-histidine 的对映体。其中 L-histidine 是婴儿必需的氨基酸，是一种线粒体谷氨酰胺转运的抑制剂。
T7454	4-Bromo-3-hydroxybenzoic acid	Decarboxylase; Endogenous Metabolite	Metabolism; Others
	4-Bromo-3-hydroxybenzoic acid 是一种组氨酸脱羧酶抑制剂，是一种 Brocresine 的代谢产物，对大鼠胎儿和大鼠胃HDC 的IC50均为 1 mM。它还能够在体外抑制猪肾脏和大鼠胃粘膜中的芳香族 L-氨基酸脱羧酶，两种酶的IC50均为 1 mM。
T22243	Anserine L-鹅肌肽,L-Anserine	Endogenous Metabolite	Metabolism
	Anserine (L-Anserine) 是 Carnosine 的甲基化形式，是口服具有活性的天然二肽，存在于脊椎动物的骨骼肌。它不会被血清肌肽酶裂解，能够作为生化缓冲液，螯合剂，抗糖化剂和抗氧化剂。它能够改善阿尔茨海默氏病模型小鼠的记忆功能。
T26480	A331440 A-331440,A331440 free base,A 331440
	A331440 is an modulator of L-histidine and histamine H3 receptor.
T37547	trans-Urocanic Acid
	trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic ...
TP1088L	N-Acetylcarnosine acetate N-Acetyl-L-carnosine acetate,N-Acetyl carnosine acetate,N-乙酰肌肽醋酸盐	Others	Others
	N-Acetylcarnosine acetate (N-Acetyl-L-carnosine acetate) 是一种天然的，含有组氨酸的二肽，是药理学上主要的 L-carnosine 的来源。N-Acetylcarnosine 是一种有效的眼科药物，有用于人类白内障的潜力。
T81935	L-Glutamic γ-monohydroxamate
	L-Glutamic γ-monohydroxamate是一种特异性抗肿瘤试剂，能够抑制癌细胞的增殖，并针对性地阻止微血管内皮细胞摄取L-组氨酸。作为钒配体，该化合物还能激活脂肪细胞对葡萄糖的摄取和代谢，进而有效降低血糖水平。
T83663	Mn(III) Protoporphyrin IX Chloride Manganese(III) Protoporphyrin IX Chloride
	Mn(III) protoporphyrin IX chloride是一种金属卟啉，当浓度为10 µM时，能在鸡胚肝细胞中诱导δ-氨基酮戊二酸合成酶和血红素加氧酶(HO)基因的mRNA表达，这些酶分别催化血红素生物合成和降解的限速步骤。Mn(III) protoporphyrin IX chloride含纳米仿生物已被用于体外纤维蛋白凝块的磁共振成像(MRI)研究。此外，它还被用于Mn(III) protoporphyrin IX-6(7)-甘氨酰-甘氨酰-L-组氨酸甲酯(MnGGH)的合成，MnGGH是一种具有微过氧化物酶活性的金属卟啉衍生物。

化合物

L-Histidine benzyl ester bistosylate

Cat.No: T40122

Target: Others

Methyl L-histidinate dihydrochloride

Cat.No: T3937

Synonym: L-Histidine methyl ester dihydrochloride,L-组氨酸甲酯二盐酸盐

Target: HDAC

L-Histidine S-malate

Cat.No: T32735

N-Formyl-L-histidine

Cat.No: T81677

Synonym: Formyl-L-histidine

N-Mercaptoacetyl-L-histidine

Cat.No: T33702

Synonym: SA 120,L-Histidine, N-(mercaptoacetyl)-,SA120,SA-120

Cat.No: T66645

Synonym: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid,(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine,FMOC-L-Histidine

N-Acetylcarnosine

Cat.No: TP1088

Synonym: N-Acetyl-L-carnosine,N-乙酰肌肽

Target: Others

N-Stearoylhistidine

Cat.No: T33760

Synonym: N-Stearoyl-L-histidine

2-Iodohistidine

Cat.No: T24974

Synonym: 2-Iodo-L-histidine

Diglycyl-histidine

Cat.No: T20382

Synonym: NSC334195,NSC-334195,Gly-gly-his,Glycylglycyl-L-histidine,NSC 334195

N-Cbz-L-histidine

Cat.No: T65767

Fmoc-1-methyl-L-histidine

Cat.No: T66680

Cat.No: T9372

Target: Mitochondrial Metabolism

4-Bromo-3-hydroxybenzoic acid

Cat.No: T7454

Target: Decarboxylase, Endogenous Metabolite

Cat.No: T22243

Synonym: L-鹅肌肽,L-Anserine

Target: Endogenous Metabolite

Cat.No: T26480

Synonym: A-331440,A331440 free base,A 331440

trans-Urocanic Acid

Cat.No: T37547

N-Acetylcarnosine acetate

Cat.No: TP1088L

Synonym: N-Acetyl-L-carnosine acetate,N-Acetyl carnosine acetate,N-乙酰肌肽醋酸盐

Target: Others

L-Glutamic γ-monohydroxamate

Cat.No: T81935

Mn(III) Protoporphyrin IX Chloride

Cat.No: T83663

Synonym: Manganese(III) Protoporphyrin IX Chloride

Cat. No.	Product Name	Target	Signaling Pathways
T2A2532	L-Histidine Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine	Mitochondrial Metabolism; Endogenous Metabolite	Metabolism
	L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T4826	L-Histidine monohydrochloride monohydrat	Others; Endogenous Metabolite	Metabolism; Others
	L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一，即蛋白质的组成部分。
T4934	1-Methyl-L-histidine 1-甲基-L-组氨酸,3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine	Endogenous Metabolite	Metabolism
	1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine)，一种人内源性代谢物，是肉类和外源性 3-methylhistidine 摄入的客观生物标记。
T8274	3-Methyl-L-histidine	Endogenous Metabolite	Metabolism
	3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。
T4732	L-Carnosine Karnozin,L-肌肽,beta-Alanyl-L-histidine	Antioxidant; Endogenous Metabolite	Metabolism; oxidation-reduction
	L-Carnosine (Karnozin) 是由beta-丙氨酸和组氨酸组成的二肽，具有抑制衰老的作用。
T38094	N-Acetyl-L-histidine monohydrate
	N-Acetyl-L-histidine monohydrate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T38094，CAS号为 39145-52-3。

天然产物

Cat.No: T2A2532

Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Target: Mitochondrial Metabolism, Endogenous Metabolite

L-Histidine monohydrochloride monohydrat

Cat.No: T4826

Target: Others, Endogenous Metabolite

1-Methyl-L-histidine

Cat.No: T4934

Synonym: 1-甲基-L-组氨酸,3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine

Target: Endogenous Metabolite

3-Methyl-L-histidine

Cat.No: T8274

Target: Endogenous Metabolite

Cat.No: T4732

Synonym: Karnozin,L-肌肽,beta-Alanyl-L-histidine

Target: Antioxidant, Endogenous Metabolite

N-Acetyl-L-histidine monohydrate

Cat.No: T38094

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02564	CARNMT1 Protein, Mouse, Recombinant (His & SUMO) Carnosine N-methyltransferase,Carnmt1	Mouse	E. coli
	N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
TMPY-01773	CNDP2 Protein, Human, Recombinant (His) CNDP dipeptidase 2 (metallopeptidase M20 f...	Human	Baculovirus-Insect Cells
	Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to thepeptidase M2A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Itmay be play a role as tumor suppressor in hepatocellular carcinoma (HCC...
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His) Carbonic Anhydrase B,Carbonate Dehydratase I,CA-I,Carbonic A...	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPY-01739	CNDP2 Protein, Mouse, Recombinant (His) C76600,Dip-2,Pep-1,Cn2,0610010E05Rik,Pep1,CNDP dipeptidase 2...	Mouse	Baculovirus-Insect Cells
	Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to thepeptidase M2A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Itmay be play a role as tumor suppressor in hepatocellular carcinoma (HCC...
TMPH-01598	CCBL2 Protein, Human, Recombinant (His & SUMO) KAT3,Kynurenine--oxoglutarate transaminase 3,CCB	Human	E. coli
	Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, seri...
TMPJ-00514	ACPP Protein, Human, Recombinant (His) Ecto-5'-Nucleotidase,TMPase,5'-Nucleotidas...	Human	Human Cells
	Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate.
TMPY-01877	CA5A Protein, Human, Recombinant (His) CA5,GS1-21A4.1,CA5AD,carbonic anhydrase VA, mitochondria...	Human	E. coli
	Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospi...
TMPY-02133	Carbonic Anhydrase VB Protein, Human, Recombinant (His) carbonic anhydrase VB, mitochondrial,CA-VB,MGC39962	Human	E. coli
	Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process...
TMPH-01604	SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. Functions as an amino acid exchanger. May play a role in the transport of L-DOPA across the blood-brain barrier. May act as the major transporter of tyrosine in fibroblasts (Probable). May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier. Ca...
TMPY-02733	CNDP1 Protein, Mouse, Recombinant (His) AI746433,carnosine dipeptidase 1 (metallop...	Mouse	HEK293
	CNDP1, also known as carnosine dipeptidase 1, glutamate carboxypeptidase-like protein 2 (CPGL-2) or carnosinase 1 (CN1), is a member of the M20 metalloprotease family. The CNDP1 gene contains trinucleotide (CTG) repeat length polymorphism in the coding region, which has been demonstrated to be associated with susceptibility to developing diabetic nephropathy, for carnosine protection against the adverse effects of high glucose levels on renal cells. In humans, CNDP1 is secreted from the liver in...
TMPY-02090	Cystatin B Protein, Human, Recombinant (His) PME,EPM1A,STFB,ULD,cystatin B (stefin B),EPM1,CST6	Human	E. coli
	Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the prot...
TMPY-00719	CNDP1 Protein, Human, Recombinant (His) HsT2308,CN1,carnosine dipeptidase 1 (metall	Human	HEK293
	CNDP1, also known as carnosine dipeptidase 1, glutamate carboxypeptidase-like protein 2 (CPGL-2) or carnosinase 1 (CN1), is a member of the M20 metalloprotease family. The CNDP1 gene contains trinucleotide (CTG) repeat length polymorphism in the coding region, which has been demonstrated to be associated with susceptibility to developing diabetic nephropathy, for carnosine protection against the adverse effects of high glucose levels on renal cells. In humans, CNDP1 is secreted from the liver in...

重组蛋白

CARNMT1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02564

Species: Mouse

Expression System: E. coli

CNDP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01773

Species: Human

Expression System: Baculovirus-Insect Cells

Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00731

Species: Human

Expression System: E. coli

CNDP2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01739

Species: Mouse

Expression System: Baculovirus-Insect Cells

CCBL2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01598

Species: Human

Expression System: E. coli

ACPP Protein, Human, Recombinant (His)

Cat.No: TMPJ-00514

Species: Human

Expression System: Human Cells

CA5A Protein, Human, Recombinant (His)

Cat.No: TMPY-01877

Species: Human

Expression System: E. coli

Carbonic Anhydrase VB Protein, Human, Recombinant (His)

Cat.No: TMPY-02133

Species: Human

Expression System: E. coli

SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01604

Species: Human

Expression System: E. coli

CNDP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02733

Species: Mouse

Expression System: HEK293

Cystatin B Protein, Human, Recombinant (His)

Cat.No: TMPY-02090

Species: Human

Expression System: E. coli

CNDP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00719

Species: Human

Expression System: HEK293

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