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Search Results for " l-histidine "
Targets Recommended: Others

20

抑制剂 & 化合物

6

天然产物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T40122 L-Histidine benzyl ester bistosylate

Others Others
L-Histidine benzyl ester bistosylate可作为HutP(一种RNA结合蛋白)的激活剂。
T3937 Methyl L-histidinate dihydrochloride

L-Histidine methyl ester dihydrochloride,L-组氨酸甲酯二盐酸盐

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) 在Sprague-Dawley 大鼠胃中组氨酸脱羧酶的抑制作用被评估为 14CO2 产生减少,活性值为 1.8 μM。
T32735 L-Histidine S-malate

L-Histidine S-malate is a bioactive chemical.
T81677 N-Formyl-L-histidine

Formyl-L-histidine

N-Formyl-L-histidine 通过与组氨酸-tRNA合成酶结合展示其活性,其Ki值为4.6 μM。此外,N-Formyl-L-histidine作为L-组氨酸解氨酶的竞争性抑制剂,具有4.26 mM的Ki值,能够有效抑制该酶对L-组氨酸的解氨反应,阻止尿苷酸的生成。
T66645 Fmoc-His-OH

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid,(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine,FMOC-L-Histidine

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid 是一种组氨酸衍生物。
T33702 N-Mercaptoacetyl-L-histidine

SA 120,L-Histidine, N-(mercaptoacetyl)-,SA120,SA-120

N-Mercaptoacetyl-L-histidine is a peptide.
TP1088 N-Acetylcarnosine

N-Acetyl-L-carnosine,N-乙酰肌肽

Others Others
N-Acetylcarnosine (N-Acetyl-L-carnosine) 是一种含有组氨酸的天然二肽,是药理学上主要的 L-carnosine 的来源。它是一种眼科药物,对人类白内障具有潜在的应用价值。
T33760 N-Stearoylhistidine

N-Stearoyl-L-histidine

N-Stearoylhistidine is a bioactive chemical.
T24974 2-Iodohistidine

2-Iodo-L-histidine

2-Iodohistidine shows potent antimalarial activity.
T20382 Diglycyl-histidine

NSC334195,NSC-334195,Gly-gly-his,Glycylglycyl-L-histidine,NSC 334195

Diglycyl-histidine is a tripeptide complexed with cupric ion designed to mimic specific Cu(II) transport site of ascorbate on albumin molecule.
T65767 N-Cbz-L-histidine

N-Cbz-L-histidine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65767。
T66680 Fmoc-1-methyl-L-histidine

Fmoc-1-methyl-L-histidine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66680,CAS号为 202920-22-7。
T9372 D-Histidine

Mitochondrial Metabolism Metabolism
D-Histidine 是一种 L-histidine 的对映体。其中 L-histidine 是婴儿必需的氨基酸,是一种线粒体谷氨酰胺转运的抑制剂。
T37547 trans-Urocanic Acid

trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic ...
T7454 4-Bromo-3-hydroxybenzoic acid

Decarboxylase; Endogenous Metabolite Metabolism; Others
4-Bromo-3-hydroxybenzoic acid 是一种组氨酸脱羧酶抑制剂,是一种 Brocresine 的代谢产物,对大鼠胎儿和大鼠胃HDC 的IC50均为 1 mM。它还能够在体外抑制猪肾脏和大鼠胃粘膜中的芳香族 L-氨基酸脱羧酶,两种酶的IC50均为 1 mM。
T22243 Anserine

L-鹅肌肽,L-Anserine

Endogenous Metabolite Metabolism
Anserine (L-Anserine) 是 Carnosine 的甲基化形式,是口服具有活性的天然二肽,存在于脊椎动物的骨骼肌。它不会被血清肌肽酶裂解,能够作为生化缓冲液,螯合剂,抗糖化剂和抗氧化剂。它能够改善阿尔茨海默氏病模型小鼠的记忆功能。
T26480 A331440

A-331440,A331440 free base,A 331440

A331440 is an modulator of L-histidine and histamine H3 receptor.
TP1088L N-Acetylcarnosine acetate

N-Acetyl-L-carnosine acetate,N-Acetyl carnosine acetate,N-乙酰肌肽醋酸盐

Others Others
N-Acetylcarnosine acetate (N-Acetyl-L-carnosine acetate) 是一种天然的,含有组氨酸的二肽,是药理学上主要的 L-carnosine 的来源。N-Acetylcarnosine 是一种有效的眼科药物,有用于人类白内障的潜力。
T81935 L-Glutamic γ-monohydroxamate

L-Glutamic γ-monohydroxamate是一种特异性抗肿瘤试剂,能够抑制癌细胞的增殖,并针对性地阻止微血管内皮细胞摄取L-组氨酸。作为钒配体,该化合物还能激活脂肪细胞对葡萄糖的摄取和代谢,进而有效降低血糖水平。
T83663 Mn(III) Protoporphyrin IX Chloride

Manganese(III) Protoporphyrin IX Chloride

Mn(III) protoporphyrin IX chloride是一种金属卟啉,当浓度为10 µM时,能在鸡胚肝细胞中诱导δ-氨基酮戊二酸合成酶和血红素加氧酶(HO)基因的mRNA表达,这些酶分别催化血红素生物合成和降解的限速步骤。Mn(III) protoporphyrin IX chloride含纳米仿生物已被用于体外纤维蛋白凝块的磁共振成像(MRI)研究。此外,它还被用于Mn(III) protoporphyrin IX-6(7)-甘氨酰-甘氨酰-L-组氨酸甲酯(MnGGH)的合成,MnGGH是一种具有微过氧化物酶活性的金属卟啉衍生物。

化合物

L-Histidine benzyl ester bistosylate
Cat.No: T40122
Synonym:
Target: Others
Methyl L-histidinate dihydrochloride
Cat.No: T3937
Synonym: L-Histidine methyl ester dihydrochloride,L-组氨酸甲酯二盐酸盐
Target: HDAC
L-Histidine S-malate
Cat.No: T32735
Synonym:
Target:
N-Formyl-L-histidine
Cat.No: T81677
Synonym: Formyl-L-histidine
Target:
Fmoc-His-OH
Cat.No: T66645
Synonym: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid,(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine,FMOC-L-Histidine
Target:
N-Mercaptoacetyl-L-histidine
Cat.No: T33702
Synonym: SA 120,L-Histidine, N-(mercaptoacetyl)-,SA120,SA-120
Target:
N-Acetylcarnosine
Cat.No: TP1088
Synonym: N-Acetyl-L-carnosine,N-乙酰肌肽
Target: Others
N-Stearoylhistidine
Cat.No: T33760
Synonym: N-Stearoyl-L-histidine
Target:
2-Iodohistidine
Cat.No: T24974
Synonym: 2-Iodo-L-histidine
Target:
Diglycyl-histidine
Cat.No: T20382
Synonym: NSC334195,NSC-334195,Gly-gly-his,Glycylglycyl-L-histidine,NSC 334195
Target:
N-Cbz-L-histidine
Cat.No: T65767
Synonym:
Target:
Fmoc-1-methyl-L-histidine
Cat.No: T66680
Synonym:
Target:
D-Histidine
Cat.No: T9372
Synonym:
Target: Mitochondrial Metabolism
trans-Urocanic Acid
Cat.No: T37547
Synonym:
Target:
4-Bromo-3-hydroxybenzoic acid
Cat.No: T7454
Synonym:
Target: Decarboxylase, Endogenous Metabolite
Anserine
Cat.No: T22243
Synonym: L-鹅肌肽,L-Anserine
Target: Endogenous Metabolite
A331440
Cat.No: T26480
Synonym: A-331440,A331440 free base,A 331440
Target:
N-Acetylcarnosine acetate
Cat.No: TP1088L
Synonym: N-Acetyl-L-carnosine acetate,N-Acetyl carnosine acetate,N-乙酰肌肽醋酸盐
Target: Others
L-Glutamic γ-monohydroxamate
Cat.No: T81935
Synonym:
Target:
Mn(III) Protoporphyrin IX Chloride
Cat.No: T83663
Synonym: Manganese(III) Protoporphyrin IX Chloride
Target:
Cat. No. Product Name Target Signaling Pathways
T2A2532 L-Histidine

Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Mitochondrial Metabolism; Endogenous Metabolite Metabolism
L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T4826 L-Histidine monohydrochloride monohydrat

Others; Endogenous Metabolite Metabolism; Others
L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一,即蛋白质的组成部分。
T4934 1-Methyl-L-histidine

1-甲基-L-组氨酸,3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine

Endogenous Metabolite Metabolism
1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine),一种人内源性代谢物,是肉类和外源性 3-methylhistidine 摄入的客观生物标记。
T8274 3-Methyl-L-histidine

Endogenous Metabolite Metabolism
3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。
T4732 L-Carnosine

Karnozin,L-肌肽,beta-Alanyl-L-histidine

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
L-Carnosine (Karnozin) 是 由beta-丙氨酸和组氨酸组成的二肽,具有抑制衰老的作用。
T38094 N-Acetyl-L-histidine monohydrate

N-Acetyl-L-histidine monohydrate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T38094,CAS号为 39145-52-3。

天然产物

L-Histidine
Cat.No: T2A2532
Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine
Target: Mitochondrial Metabolism, Endogenous Metabolite
L-Histidine monohydrochloride monohydrat
Cat.No: T4826
Synonym:
Target: Others, Endogenous Metabolite
1-Methyl-L-histidine
Cat.No: T4934
Synonym: 1-甲基-L-组氨酸,3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine
Target: Endogenous Metabolite
3-Methyl-L-histidine
Cat.No: T8274
Synonym:
Target: Endogenous Metabolite
L-Carnosine
Cat.No: T4732
Synonym: Karnozin,L-肌肽,beta-Alanyl-L-histidine
Target: Antioxidant, Endogenous Metabolite
N-Acetyl-L-histidine monohydrate
Cat.No: T38094
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-02564 CARNMT1 Protein, Mouse, Recombinant (His & SUMO)

Carnosine N-methyltransferase,Carnmt1

Mouse E. coli
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
TMPJ-00731 Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Carbonic Anhydrase B,Carbonate Dehydratase I,CA-I,Carbonic A...

Human E. coli
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPY-01877 CA5A Protein, Human, Recombinant (His)

CA5,GS1-21A4.1,CA5AD,carbonic anhydrase VA, mitochondria...

Human E. coli
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospi...
TMPJ-00514 ACPP Protein, Human, Recombinant (His)

Ecto-5'-Nucleotidase,TMPase,5'-Nucleotidas...

Human HEK293 Cells
Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate.
TMPY-02133 Carbonic Anhydrase VB Protein, Human, Recombinant (His)

carbonic anhydrase VB, mitochondrial,CA-VB,MGC39962

Human E. coli
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process...
TMPY-02090 Cystatin B Protein, Human, Recombinant (His)

PME,EPM1A,STFB,ULD,cystatin B (stefin B),EPM1,CST6

Human E. coli
Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the prot...

重组蛋白

CARNMT1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02564
Species: Mouse
Expression System: E. coli
Carbonic Anhydrase 1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00731
Species: Human
Expression System: E. coli
CA5A Protein, Human, Recombinant (His)
Cat.No: TMPY-01877
Species: Human
Expression System: E. coli
ACPP Protein, Human, Recombinant (His)
Cat.No: TMPJ-00514
Species: Human
Expression System: HEK293 Cells
Carbonic Anhydrase VB Protein, Human, Recombinant (His)
Cat.No: TMPY-02133
Species: Human
Expression System: E. coli
Cystatin B Protein, Human, Recombinant (His)
Cat.No: TMPY-02090
Species: Human
Expression System: E. coli
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