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Search Results for " is-159 "

Targets Recommended: Others

16

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T27628	IS-159 IS 159,IS159	Others	Others
	IS-159, a 5-HT1D agonist, is used potentially for the treatment of migraine.
T5100	DJ-V-159 DJ-V159	GPR; Androgen Receptor	Endocrinology/Hormones; GPCR/G Protein
	DJ-V-159 (DJ-V159) 是一种G 蛋白偶联受体家族C 组6 A 的激动剂。
T4043	ETC-159 ETC159,ETC-1922159,ETC 159	Wnt/beta-catenin; Porcupine	Cytoskeletal Signaling; Stem Cells
	ETC-159 (ETC-1922159) 是一种具有口服活性的，有效 PORCN 抑制剂。抑制β-catenin 报告基因活性的 IC50值为2.9 nM。
T29034	U75302 U 75302,U-75302	Others	Others
	U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.
T11309	FMF-04-159-2	CDK	Cell Cycle/Checkpoint
	FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively. FMF-04-159-2 is a covalent CDK14 inhibitor.
T79774	Antibacterial agent 159	Antibiotic	Microbiology/Virology
	Antibacterialagent 159 (Compound 6d) 是一款高效抗菌化合物，具备针对脓疱疮和C. difficile感染（CDI）的抗菌活性。其使用过程中未发现C. difficile复发现象，并对益生肠道菌群仅有微弱影响。
T15021	CV-159	Others	Others
	CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.
T80099	Ovalbumin (154-159)	Angiotensin-converting Enzyme (ACE)	Metabolism
	Ovalbumin (154-159)为卵清蛋白片段，同时作为一种有效的血管紧张素转换酶 (ACE) 抑制剂，适用于高血压研究。
T62894	AZ-PFKFB3-67 quarterhydrate	Others	Others
	AZ-PFKFB3-67 quarterhydrate 是一种选择性的、高效的代谢激酶 PFKFB3 激酶抑制剂，作用于 PFKFB3 (IC50: 11 nM)、PFKFB2 (IC50: 159 nM) 和 PFKFB1 (IC50: 1130 nM)。
T32337	JWH-167 JWH 167,JWH167	Others	Others
	JWH 167, a synthetic cannabinoid (CB), has moderate affinities for central CB1 (Ki = 90 nM) and peripheral CB2 (Ki = 159 nM) receptors. Its physiological and toxicological properties have not been evaluated. This product is only applied for forensic and r
T13743	JH-XI-10-02	EGFR; PROTACs	Angiogenesis; JAK/STAT signaling; PROTAC; Tyrosine Kinase/Adaptors
	JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19. JH-XI-10-02 is a potent and selective degrader of CDK8, with an IC50 of 159 nM, based on PROTAC.
T39815	anti-TNBC agent-1	Others	Others
	anti-TNBC agent-1 is a highly effective compound specifically designed to target and combat triple-negative breast cancer (TNBC). It demonstrates remarkable potency against various breast cancer cell types, with IC50 values spanning from 0.20 μM to 0.27 μM. The mechanism of action of anti-TNBC agent-1 involves inducing apoptosis in SUM-159 cells through the mitochondria pathway, as well as causing G1 phase arrest in these cells.
T35671	Salazinic Acid	Others	Others
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30.8 mM). Salazinic acid is cytotoxic to MM98, A431, and HaCaT cells in crystal violet (EC50s = 159, 2,870, and 48 μM, respectively) and neutral red uptake assays (EC50s = 1,925, 1,913, and 907 μM, respectively).2 It increases the wound closure rate in scratch-wounded HaCaT monolay...
T36691	Erythromycin 2'-Propionate	Others	Others
	Erythromycin 2'-propionate is a macrolide antibiotic and an esterified form of erythromycin .1It is active againstS. aureuswhen used at a concentration of 1 μg/ml. Erythromycin 2'-propionate (1 mM) inhibits protein synthesis in a cell-free assay. 1.Tardrew, P.L., Mao, J.C.H., and Kenney, D.Antibacterial activity of 2'-esters of erythromycinAppl. Microbiol.18(2)159-165(1969)
T36137	Biotin (S)-sulfoxide	Others	Others
	Biotin (S)-sulfoxide is an inactive metabolite of the coenzyme biotin .1,2It has also been found inE. coliand is reduced by the biotin sulfoxide reduction system as a source of biotin.3 1.Denkel, L.A., Rhen, M., and Bange, F.-C.Biotin sulfoxide reductase contributes to oxidative stress tolerance and virulence in Salmonella enterica serovar TyphimuriumMicrobiology (Reading)159(Pt 7)1447-1458(2013) 2.Carling, R.S., and Turner, C.Methods for assessment of biotin (Vitamin B7)Laboratory assessment of...
T38123	5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
	5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production. 1.Hempel, S.L., Buettner, G.R....

化合物

Cat.No: T27628

Synonym: IS 159,IS159

Target: Others

Cat.No: T5100

Synonym: DJ-V159

Target: GPR, Androgen Receptor

Cat.No: T4043

Synonym: ETC159,ETC-1922159,ETC 159

Target: Wnt/beta-catenin, Porcupine

Cat.No: T29034

Synonym: U 75302,U-75302

Target: Others

Cat.No: T11309

Target: CDK

Antibacterial agent 159

Cat.No: T79774

Target: Antibiotic

Cat.No: T15021

Target: Others

Ovalbumin (154-159)

Cat.No: T80099

Target: Angiotensin-converting Enzyme (ACE)

AZ-PFKFB3-67 quarterhydrate

Cat.No: T62894

Target: Others

Cat.No: T32337

Synonym: JWH 167,JWH167

Target: Others

Cat.No: T13743

Target: EGFR, PROTACs

anti-TNBC agent-1

Cat.No: T39815

Target: Others

Cat.No: T35671

Target: Others

Erythromycin 2'-Propionate

Cat.No: T36691

Target: Others

Biotin (S)-sulfoxide

Cat.No: T36137

Target: Others

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

Cat.No: T38123

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00334	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) TGF-β receptor type II,Tgfbr2,TGF-β receptor type-2,TGF-β ty...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.

重组蛋白

TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

Cat.No: TMPJ-00334

Species: Mouse

Expression System: HEK293 Cells

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