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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36800 EN219

EN219 is a synthetic recruiter of the E3 ubiquitin ligase RNF114.1It binds to cysteine 8 (C8) in the intrinsically disordered region of RNF114 (RNF114-C8; IC50= 470 nM) and inhibits RNF114-induced autoubiquitination and p21 ubiquitination in a cell-free assay when used at a concentration of 50 μM. EN219 (1 μM) also interacts with cysteine residues in the tubulin β1 chain (TUBB1), heat shock protein 60 (Hsp60), also known as Hsp family D member 1 (HspD1), and histone H3.1 (HIST1H3A) in 231MFP hum...

化合物

EN219
Cat.No: T36800
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02580 Histone H1 Protein, Human, Recombinant (His)

HSP60,HSP65,CPN60,H1 histone family, member 0,H...

Human E. coli
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes, all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-termin...
TMPY-01577 ORP150 Protein, Human, Recombinant (His)

hypoxia up-regulated 1,HSP12A,Grp1

Human HEK293 Cells
Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four different heat shock protein (HSP) families were identified including HYOU1 (ORP15), HSPC1 (HSP86), HSPA5 (Bip), HSPD1 (HSP6), and several isoforms of the two testis-specific HSP7 chaperones HSPA2 and HSPA1L. HYOU1 is highly expressed in tissues that contain well-developed endoplasmic re...

重组蛋白

Histone H1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02580
Species: Human
Expression System: E. coli
ORP150 Protein, Human, Recombinant (His)
Cat.No: TMPY-01577
Species: Human
Expression System: HEK293 Cells
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