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Targets Recommended: PI3K

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Cat. No. Product Name Target Signaling Pathways
T1988 Duvelisib

INK1197,IPI-145,度维利塞

PI3K PI3K/Akt/mTOR signaling
Duvelisib (INK1197) 是 p100δ的选择性抑制剂,能够作用于 p110δ (IC50:2.5 nM)、p110γ (IC50:27.4 nM)、p110β (IC50:85 nM) 和 p110α (IC50:1602 nM)。
T11129L Duvelisib (R enantiomer) hydrochloride

IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl

PI3K PI3K/Akt/mTOR signaling
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) 是 PI3K 抑制剂。Duvelisib (R enantiomer) hydrochloride 是 Duvelisib 的活性较低的对映体。
T11129 Duvelisib (R enantiomer)

Duvelisib R enantiomer,IPI-145 R enantiomer,INK1197 R enantiomer

PI3K PI3K/Akt/mTOR signaling
Duvelisib R enantiomer (IPI-145 R enantiomer) 是一种 Duvelisib 的对映异构体,活性较低。 它是一种 PI3K 抑制剂。
T70802 Duvelisib hydrate

Others Others
Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike oth...
T70800 Elenbecestat free base

Others Others
Elenbecestat,also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.

化合物

Duvelisib
Cat.No: T1988
Synonym: INK1197,IPI-145,度维利塞
Target: PI3K
Duvelisib (R enantiomer) hydrochloride
Cat.No: T11129L
Synonym: IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl
Target: PI3K
Duvelisib (R enantiomer)
Cat.No: T11129
Synonym: Duvelisib R enantiomer,IPI-145 R enantiomer,INK1197 R enantiomer
Target: PI3K
Duvelisib hydrate
Cat.No: T70802
Synonym:
Target: Others
Elenbecestat free base
Cat.No: T70800
Synonym:
Target: Others
TargetMol Loading
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