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Search Results for " casp10 "

Targets Recommended: Caspase

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T70038	MJN68390	Caspase	Apoptosis; Proteases/Proteasome
	MJN68390 对 CASP8 的表观 IC50值为 15 μM，对 CASP10 不显示活性。

化合物

Cat.No: T70038

Target: Caspase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His) CASP10,FAS-Associated Death Domain Protein...	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca...
TMPH-02335	RIOK3 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3. Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling. Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway. May play a role in the biogenesis of the ...
TMPH-01057	Caspase-8 Protein, Human, Recombinant (His) Caspase-8,CAP4,Apoptotic cysteine protease,FLICE,FA...	Human	E. coli
	Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood. Initiator protease that induces extrinsic apoptosis by mediating cleavage and activation of effector caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. Binding ...

重组蛋白

Caspase-10 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01256

Species: Human

Expression System: E. coli

RIOK3 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02335

Species: Human

Expression System: E. coli

Caspase-8 Protein, Human, Recombinant (His)

Cat.No: TMPH-01057

Species: Human

Expression System: E. coli

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