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11
5
Cat. No. | Product Name | ||
---|---|---|---|
CL0147 | c-FMS inhibitor kit | ||
CL0094 | FLT3 inhibitor kit | ||
CL0058 | EGFR inhibitor kit | ||
L7900 | 成骨分子库 | 320 compounds | |
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening; | |||
L9600 | 多肽分子库 | 533 compounds | |
533 peptides can be used in peptide drug development and signaling transduction and mechanism study; | |||
L4710 | 非甾体类抗炎化合物库 | 530 compounds | |
530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening. | |||
L6300 | 药食同源库 | 1088 compounds | |
A unique collection of 1088 compounds from food as medicine for high throughput and high content screening; | |||
L8500 | HIF-1化合物库 | 1352 compounds | |
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; | |||
L2191 | 抗乳腺癌化合物库 | 1965 compounds | |
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study; | |||
L9420 | 外泌体相关化合物库 | 54 compounds | |
54 exosome-related compounds that can be used for high-throughput and high-content screening. | |||
L9410 | 共价抑制剂库 | 941 compounds | |
A unique collection of 941 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc. |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0003 |
Phosphatase Inhibitor Cocktail II (100× DMSO)
磷酸酶抑制剂 Cocktail II |
Solution (100× in DMSO) | Alkaline phosphatases, Ser/Thr phosphatases, Acid and PP1 and PP2A |
C0002 |
Phosphatase Inhibitor Cocktail I (100× ddH2O)
磷酸酶抑制剂 Cocktail I |
Solution (100× in ddH2O) | Acid Phosphatase, Alkaline phosphatase, PTPs, ATPases |
C0004 |
Phosphatase Inhibitor Cocktail III (2 Tubes, 100x)
磷酸酶抑制剂 Cocktail III |
2 Tube Solution (100×) | Each Tube has different specificity of inhibition |
C0045 |
RIPA Lysis Buffer (Strong)
RIPA Lysis Buffer (Strong) |
||
C0001 |
Protease Inhibitor Cocktail
蛋白酶抑制剂 Cocktail |
Solution (EDTA-Free,100× in DMSO) | Serine proteases, Aminopeptidases, Cysteine proteases, Aspartic proteases |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8470 | BMS-1001 | PD-1/PD-L1 | Immunology/Inflammation; Apoptosis; Cell Cycle/Checkpoint |
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay). | |||
T10565 | BMS-1001 hydrochloride | PD-1/PD-L1 | Apoptosis; Immunology/Inflammation; Cell Cycle/Checkpoint |
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes. |