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Search Results for "BMS-1001"
Targets Recommended: PD-1/PD-L1

2

抑制剂 & 化合物

11

化合物库

5

TargetMol 试剂盒

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Cat. No. Product Name
CL0147 c-FMS inhibitor kit

CL0094 FLT3 inhibitor kit

CL0058 EGFR inhibitor kit

L7900 成骨分子库

320 compounds
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening;
L9600 多肽分子库

533 compounds
533 peptides can be used in peptide drug development and signaling transduction and mechanism study;
L4710 非甾体类抗炎化合物库

530 compounds
530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.
L6300 药食同源库

1088 compounds
A unique collection of 1088 compounds from food as medicine for high throughput and high content screening;
L8500 HIF-1化合物库

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
L2191 抗乳腺癌化合物库

1965 compounds
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;
L9420 外泌体相关化合物库

54 compounds
54 exosome-related compounds that can be used for high-throughput and high-content screening.
L9410 共价抑制剂库

941 compounds
A unique collection of 941 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.

化合物库

c-FMS inhibitor kit
CL0147
Compounds: 0
FLT3 inhibitor kit
CL0094
Compounds: 0
EGFR inhibitor kit
CL0058
Compounds: 0
成骨分子库
L7900
Compounds: 320
多肽分子库
L9600
Compounds: 533
非甾体类抗炎化合物库
L4710
Compounds: 530
药食同源库
L6300
Compounds: 1088
HIF-1化合物库
L8500
Compounds: 1352
抗乳腺癌化合物库
L2191
Compounds: 1965
外泌体相关化合物库
L9420
Compounds: 54
共价抑制剂库
L9410
Compounds: 941
Cat. No. Product Name Form Specificity Of Inhibition
C0003 Phosphatase Inhibitor Cocktail II (100× DMSO)

磷酸酶抑制剂 Cocktail II

Solution (100× in DMSO) Alkaline phosphatases, Ser/Thr phosphatases, Acid and PP1 and PP2A
C0002 Phosphatase Inhibitor Cocktail I (100× ddH2O)

磷酸酶抑制剂 Cocktail I

Solution (100× in ddH2O) Acid Phosphatase, Alkaline phosphatase, PTPs, ATPases
C0004 Phosphatase Inhibitor Cocktail III (2 Tubes, 100x)

磷酸酶抑制剂 Cocktail III

2 Tube Solution (100×) Each Tube has different specificity of inhibition
C0045 RIPA Lysis Buffer (Strong)

RIPA Lysis Buffer (Strong)

C0001 Protease Inhibitor Cocktail

蛋白酶抑制剂 Cocktail

Solution (EDTA-Free,100× in DMSO) Serine proteases, Aminopeptidases, Cysteine proteases, Aspartic proteases

TargetMol 试剂盒

磷酸酶抑制剂 Cocktail II
C0003
磷酸酶抑制剂 Cocktail I
C0002
磷酸酶抑制剂 Cocktail III
C0004
RIPA Lysis Buffer (Strong)
C0045
蛋白酶抑制剂 Cocktail
C0001
Cat. No. Product Name Target Signaling Pathways
T8470 BMS-1001

PD-1/PD-L1 Immunology/Inflammation; Apoptosis; Cell Cycle/Checkpoint
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
T10565 BMS-1001 hydrochloride

PD-1/PD-L1 Apoptosis; Immunology/Inflammation; Cell Cycle/Checkpoint
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.

化合物

BMS-1001
T8470
synonym:
Target: PD-1/PD-L1
BMS-1001 hydrochloride
T10565
synonym:
Target: PD-1/PD-L1