2thiouridine

2-Thiouridine（s2U）是一种天然存在于转运 RNA 中的修饰核苷碱基，可稳定 U:A 碱基配对，同时适度削弱 U:G 摆动配对。2-Thiouridine 影响密码子–反密码子识别、翻译准确性及 RNA 构象动力学，并被广泛用于核酸结构、RNA 生物学及功能性 RNA 生物分子工程研究。

2'-O-Methyl-2-thiouridine 是一种存在于合成嗜热细菌tRNA中的嘌呤核苷类似物。2'-O-Methyl-2-thiouridine 对 A 的选择性高于未修饰的 U。

2-Thio-UTP是一种选择性的P2Y2受体(Purinergic Receptor)激动剂(EC50=50 nM),能够抑制瓣膜间质细胞（VIC）的钙化电位，α-平滑肌肌动蛋白表达和促纤维化基因表达,可用于研究钙化性主动脉瓣狭窄(CAVS)。

3’-β-C-Methyl-2-thiouridine 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要通过抑制DNA合成及诱导细胞凋亡（apoptosis）等机制，靶向惰性淋巴系统恶性肿瘤。

5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Amino nucleoside; Thio-nucleoside.

5-Methoxycarbonylmethyl-2-thiouridine is a Nucleoside Derivative - Thio-nucleoside, 5-Modified pyrimidine nucleoside;Naturally modified ribo-nucleoside.

2'-C-Methyl-2-thiouridine is a Nucleoside Derivative - Thio-nucleoside, 2'-Modified nucleoside.

Nucleoside Derivatives - Fluoro-modified nucleosides, 3'-Modified nucleosides, Thio-nucleosides

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides, Thio-nucleosides

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Naturally modified Ribo-nucleosides

5-Methyl-2-thiouridine是一种嘌呤核苷类似物，可用于生物化学实验和药物合成研究。

Nucleoside Derivatives - Fluoro-modified nucleosides, 2'-Modified nucleosides, Thio-nucleosides

Nucleoside Derivatives - Azido-nucleosides; Thio-nucleosides; 3'-Modified nucleosides

Nucleoside Derivatives - 4'-Modified nucleosides; Thio-nucleosides

5'(R)-C-Methyl-2-thiouridine is a Nucleoside Derivative - 5'-Modified nucleoside.

3'-Deoxy-methyl-2-thiouridine is a Nucleoside Derivative - 3'-Deoxy nucleoside; Thio-nucleoside.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; 2-Thio-nucleosides

Nucleoside Derivatives - 3'-Modified nucleosides; Thio-nucleosides

Nucleoside Derivatives - Thio-nucleosides; 3'-Modified nucleosides

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Amino nucleosides; Naturally modified ribo-nucleosides

Thio-nucleoside; 5-modified nucleoside

Thio-nucleoside, 5-modified nucleoside

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides

Nucleosides Derivatives –Thio-nucleosides