转化生长因子-β 家族

转化生长因子-β (Transforming Growth Factor-β, TGF-β) 是一种多功能细胞因子，属于转化生长因子超家族，包括三种不同的哺乳动物亚型（TGF-β 1~3，HGNC编号TGFB1、TGFB2、TGFB3）和许多其他信号蛋白。TGFB 蛋白由所有白细胞谱系产生。活化的 TGF-β 复合物与其他因子形成与 TGF-β 受体结合的丝氨酸/苏氨酸激酶复合物。TGF-β受体由1型和2型受体亚基组成。TGF-β结合后，2型受体激酶磷酸化并激活1型受体激酶，从而激活信号级联反应。TGF-β在干细胞分化以及T细胞调控和分化中也起着至关重要的作用。由于其在免疫和干细胞调控和分化中的作用，它是癌症、自身免疫性疾病和传染病领域中研究最多的细胞因子。

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Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-00100	Artemin Protein, Human, Recombinant Artemin Protein, Human, Recombinant	Human	E. coli
TMPJ-00100	Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a varia...
TMPJ-00238	Lefty-A Protein, Human, Recombinant (His) Lefty-A Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00238	Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated...
TMPJ-00250	LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
TMPJ-00250	Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-te...
TMPJ-00255	TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated	Human	Human Cells
TMPJ-00255	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell...
TMPJ-00256	Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
TMPJ-00256	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell...
TMPJ-00259	TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated	Human	Human Cells
TMPJ-00259	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell...
TMPJ-00260	Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
TMPJ-00260	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell...
TMPJ-00271	SMAD3 Protein, Human, Recombinant (His & Flag) SMAD3 Protein, Human, Recombinant (His & Flag)	Human	E. coli
TMPJ-00271	Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocati...
TMPJ-00622	Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
TMPJ-00622	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell...
TMPJ-00663	GDF-8 Protein, Human/Mouse/Rat, Recombinant GDF-8 Protein, Human/Mouse/Rat, Recombinant	Human,Mouse,Rat	Human Cells
TMPJ-00663	Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is c...
TMPJ-00713	GDF-11 Protein, Human, Recombinant GDF-11 Protein, Human, Recombinant	Human	Human Cells
TMPJ-00713	Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-poster...
TMPJ-00771	TGF beta 1 Protein, Mouse/Rat, Recombinant TGF beta 1 Protein, Mouse/Rat, Recombinant	Mouse,Rat	Human Cells
TMPJ-00771	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular...
TMPJ-00772	Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	Human Cells
TMPJ-00772	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell...
TMPJ-00966	GDF-5 Protein, Human, Recombinant GDF-5 Protein, Human, Recombinant	Human	E. coli
TMPJ-00966	Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the ...
TMPJ-01015	INHBC Protein, Human, Recombinant (C-His) INHBC Protein, Human, Recombinant (C-His)	Human	Human Cells
TMPJ-01015	Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through associatio...
TMPJ-01016	INHBC Protein, Human, Recombinant (N-His) INHBC Protein, Human, Recombinant (N-His)	Human	E. coli
TMPJ-01016	Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ ...
TMPJ-01108	SMAD4 Protein, Human, Recombinant (His) SMAD4 Protein, Human, Recombinant (His)	Human	E. coli
TMPJ-01108	SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD ho...
TMPJ-01226	Irisin Protein, Human/Mouse/Rat, Recombinant (hFc) Irisin Protein, Human/Mouse/Rat, Recombinant (hFc)	Human,Mouse,Rat	Human Cells
TMPJ-01226	Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene.Human Irisin is synthesized as a 212 am...
TMPJ-01227	Irisin Protein, Human/Mouse/Rat, Recombinant (C-His) Irisin Protein, Human/Mouse/Rat, Recombinant (C-His)	Human,Mouse,Rat	Human Cells
TMPJ-01227	Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene.Human Irisin is synthesized as a 212 am...
TMPJ-01228	Irisin Protein, Human/Mouse/Rat, Recombinant (N-His) Irisin Protein, Human/Mouse/Rat, Recombinant (N-His)	Human,Mouse,Rat	Human Cells
TMPJ-01228	Irisin Protein, Human/Mouse/Rat, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18-28 KDa and the...

Artemin Protein, Human, Recombinant

Cat.No: TMPJ-00100

Species: Human

Expression System: E. coli