单克隆抗体是由单个B 淋巴细胞克隆所分泌的抗体,由于B 淋巴细胞只能产生一种专有的、针对一种抗原决定簇的抗体,所以具有理化性质高度专一、生物活性单一、与抗原结合特异性强等特点。因此,它也被形象地被称为“生物导弹”, 现有的抗体药物大多属于此类抗体。近年来,单克隆抗体药物迅速发展,并逐渐成为生物医药领域发展的主要方向。
TargetMol可为您提供30多种抗体抑制剂,满足您的实验需求。TargetMol始终致力于服务“科研人员”,将热门的研究报道和产品推送给各位科研人员。
Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T36653 | Anti-SARS-80R mAb
Anti-SARS-80R mAb
|
98% |
|
|
Anti-SARS-80R mAb (SARS-80R) is a human IgG1 monoclonal antibody that is derived from CHO cells. Its main function is to selectively bind to the Spike (S1) prote... | ||||
T36654 | Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022)
|
98% |
|
|
Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both... | ||||
T35394 | Sintilimab (anti-PD-1)
Sintilimab (anti-PD-1)
|
98% |
|
|
Sintilimab (anti-PD-1, IBI 308) 是一种全人源 IgG4 单克隆抗体,可与 T 细胞表面的 PD-1结合,阻断 PD-1/PD-配体 1 (PD-L1) 通路,并重新激活 T 细胞以杀死癌细胞。 | ||||
T9914 | Vedolizumab
维多珠单抗
|
943609-66-3 | 98% |
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Vedolizumab 是一种人源化单克隆抗体,靶向α4β7整联蛋白,用于溃疡性结肠炎和克罗恩病的相关研究。 | ||||
T35397 | Sacituzumab (anti-Trop-2)
Sacituzumab (anti-Trop-2)
|
1796566-95-4 | 98% |
|
Sacituzumab 是一种人源化 IgG1 单克隆抗体,与抗滋养层细胞表面抗原 2 (anti-Trop-2) 结合。Sacituzumab 具有用于转移性三阴性乳腺癌研究的潜力。 | ||||
T11126 | Durvalumab
德瓦鲁单抗
|
1428935-60-7 | 98% |
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Durvalumab is an anti-PD-L1 monoclonal antibody, humanized.Durvalumab completely blocked the binding of PD-L1 to PD-1 and CD80, and the IC50s were 0.1 and 0.04 n... | ||||
T9923 | Nimotuzumab
尼妥珠单抗
|
828933-51-3 | 98% |
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Nimotuzumab 是一种针对表皮生长因子受体 EGFR 的人源化治疗性单克隆抗体。 | ||||
T36651 | Anti-MERS-2E6 mAb
Anti-MERS-2E6 mAb
|
98% |
|
|
Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to ... | ||||
T9904 | Bevacizumab
贝伐珠单抗
|
216974-75-3 | 98% |
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Bevacizumab 是人源化的单克隆抗体,能够高亲和力的、特异性的与所有 VEGF-A 结合。 | ||||
T38951 | Isatuximab
Isatuximab
|
1461640-62-9 | 98% |
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Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38 , a protein highly expressed on hematological malignant cells, inclu... | ||||
T36655 | Anti-Spike-RBD mAb
Anti-Spike-RBD mAb
|
98% |
|
|
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach f... | ||||
T9922 | Matuzumab
马妥珠单抗
|
339186-68-4 | 98% |
|
Matuzumab 是一种用于癌症治疗的人源化单克隆抗体。它对 EGFR 具有高亲和力,通常与恶性肿瘤中血管的生长有关,从而促进肿瘤的生长和存活。 | ||||
T35389 | Sarilumab (anti-IL-6Rα)
Sarilumab (anti-IL-6Rα)
|
98% |
|
|
Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体,与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。 | ||||
T36656 | Anti-Spike-RBD Single Domain mAb
Anti-Spike-RBD Single Domain mAb
|
98% |
|
|
The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the... | ||||
T12706 | Reslizumab
化合物 T12706
|
241473-69-8 | 98% |
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Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. | ||||
T39057 | Rozanolixizumab
Rozanolixizumab
|
1584645-37-3 | 98% |
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Rozanolixizumab (UCB7665) is a humanized monoclonal antibody (IgG4P) that exhibits high affinity for the human neonatal Fc receptor (FcRn). Its application lies ... | ||||
T9931 | Meplazumab
化合物meplazumab
|
2413715-21-4 | 98% |
|
meplazumab 是一种人源化抗 CD147 抗体,作为 COVID-19 肺炎患者的附加疗法。 | ||||
T36652 | Anti-MERS-3A1 mAb
Anti-MERS-3A1 mAb
|
98% |
|
|
Anti-MERS-3A1 mAb (MERS-3A1) is a high-affinity human monoclonal IgG1 antibody derived from CHO cells. It effectively inhibits the interaction between the MERS-C... | ||||
T35396 | Spartalizumab (anti-PD-1)
Spartalizumab (anti-PD-1)
|
98% |
|
|
Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性;MW: 145.8 KD。 | ||||
T9917 | Denosumab
地诺单抗
|
615258-40-7 | 98% |
|
Denosumab 是能够结合并抑制RANKL 受体激活因子的人单克隆抗体。它具有抗癌活性,可降髋部、低椎骨以及非椎骨骨折的风险。 |