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抗体

单克隆抗体是由单个B 淋巴细胞克隆所分泌的抗体,由于B 淋巴细胞只能产生一种专有的、针对一种抗原决定簇的抗体,所以具有理化性质高度专一、生物活性单一、与抗原结合特异性强等特点。因此,它也被形象地被称为“生物导弹”, 现有的抗体药物大多属于此类抗体。近年来,单克隆抗体药物迅速发展,并逐渐成为生物医药领域发展的主要方向。

TargetMol可为您提供 xnum 多种抗体抑制剂,满足您的实验需求。TargetMol始终致力于服务“科研人员”,将热门的研究报道和产品推送给各位科研人员。

Cat. No. Product Name CAS No. Purity Chemical Structure
T78269 Anti-Mouse PD-1 Antibody (RMP1-14)
抗体Anti-Mouse PD-1 Antibody (RMP1-14)
98.01%
Anti-Mouse PD-1 Antibody (RMP1-14)
RMP1-14 是一种 IgG1 样免疫球蛋白抗小鼠 PD-1 抗体,可阻断 PD-1/PD-L1 信号传导。
T9920 Evolocumab
依洛尤单抗
1256937-27-5 98%
Evolocumab
Evolocumab 是人源化单克隆抗体PCSK9的抑制剂。它与循环的 PCSK9 蛋白结合,使得PCSK9与 LDLR 结合受到抑制。它可用研究于高胆固醇血症以及动脉粥样硬化性心血管疾病的研究。
T9923 Nimotuzumab
尼妥珠单抗
828933-51-3 95.00%
TargetMol Chemical Structure Nimotuzumab
Nimotuzumab 是一种针对表皮生长因子受体 EGFR 的人源化治疗性单克隆抗体。
T36653 Anti-SARS-80R mAb
Anti-SARS-80R mAb
98%
Anti-SARS-80R mAb
Anti-SARS-80R mAb (SARS-80R) is a human IgG1 monoclonal antibody that is derived from CHO cells. Its main function is to selectively bind to the Spike (S1) prote...
T36654 Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022)
98%
Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both...
T36651 Anti-MERS-2E6 mAb
Anti-MERS-2E6 mAb
98%
Anti-MERS-2E6 mAb
Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to ...
T36655 Anti-Spike-RBD mAb
Anti-Spike-RBD mAb
98%
Anti-Spike-RBD mAb
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach f...
T9922 Matuzumab
马妥珠单抗
339186-68-4 98%
Matuzumab
Matuzumab 是一种用于癌症治疗的人源化单克隆抗体。它对 EGFR 具有高亲和力,通常与恶性肿瘤中血管的生长有关,从而促进肿瘤的生长和存活。
T35389 Sarilumab (anti-IL-6Rα)
Sarilumab (anti-IL-6Rα)
98%
Sarilumab (anti-IL-6Rα)
Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体,与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。
T36656 Anti-Spike-RBD Single Domain mAb
Anti-Spike-RBD Single Domain mAb
98%
Anti-Spike-RBD Single Domain mAb
The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the...
T12706 Reslizumab
化合物 T12706
241473-69-8 98%
TargetMol Chemical Structure Reslizumab
Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma.
T9931 Meplazumab
化合物meplazumab
2413715-21-4 98%
meplazumab
meplazumab 是一种人源化抗 CD147 抗体,作为 COVID-19 肺炎患者的附加疗法。
T36652 Anti-MERS-3A1 mAb
Anti-MERS-3A1 mAb
98%
Anti-MERS-3A1 mAb
Anti-MERS-3A1 mAb (MERS-3A1) is a high-affinity human monoclonal IgG1 antibody derived from CHO cells. It effectively inhibits the interaction between the MERS-C...
T35396 Spartalizumab (anti-PD-1)
Spartalizumab (anti-PD-1)
98%
Spartalizumab (anti-PD-1)
Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性;MW: 145.8 KD。
T76559 Survodutide
化合物Survodutide
2805997-46-8 99.83%
TargetMol Chemical Structure Survodutide
Survodutide (BI 456906) 是一种胰高血糖素和胰高血糖素样肽 1 (GLP-1) 受体 (GLP Receptor) 双重激动剂,可降低 HbA1c16 型糖尿病的体重。
T9908 Pembrolizumab
派姆單抗
1374853-91-4 99.70%
Pembrolizumab
Pembrolizumab 是一种抑制 PD-1 受体的人源化单克隆抗体,是一个 HER2 二聚化抑制剂类,它会削弱 HER2 与 HER 家族其他成员结合的能力。
T9921 Infliximab
英夫利昔单抗
170277-31-3 99.70%
TargetMol Chemical Structure Infliximab
Infliximab 是一种与 TNF-α特异性结合的嵌合单克隆 IgG1 抗体,可阻止 TNF-α与 TNFR1和 TNFR2 的相互作用,用于治疗克罗恩病和类风湿性关节炎。
T9906 Ipilimumab
伊匹单抗
477202-00-9 99.60%
TargetMol Chemical Structure Ipilimumab
Ipilimumab 是全人类单克隆抗体 IgG1κ,能够抗 CTLA-4。其中CTLA-4是一种由活化的 T 细胞产生的免疫抑制分子。
T9911 Tocilizumab
托珠单抗
375823-41-9 99.50%
TargetMol Chemical Structure Tocilizumab
Tocilizumab 是抗人白细胞介素-6 受体 (IL-6R) 的中和抗体,能够阻碍 IL-6 与 IL-6R 的结合,进而抑制经典和反式信号。它可用于研究类风湿性关节炎,对重症 COVID-19 冠状病毒病方面的研究具有显著效果。
T9930 Secukinumab
苏金单抗
875356-43-7 99.10%
Secukinumab
Secukinumab 是一种完全人源化的单克隆抗 IL-17A 抗体,是一个被美国食品和药物管理局批准用于治疗中度至重度斑块型银屑病的抗体。
Anti-Mouse PD-1 Antibody (RMP1-14)
T78269
RMP1-14 是一种 IgG1 样免疫球蛋白抗小鼠 PD-1 抗体,可阻断 PD-1/PD-L1 信号传导。
Evolocumab
T9920
Evolocumab 是人源化单克隆抗体PCSK9的抑制剂。它与循环的 PCSK9 蛋白结合,使得PCSK9与 LDLR 结合受到抑制。它可用研究于高胆固醇血症以及动脉粥样硬化性心血管疾病的研究。
Nimotuzumab
T9923
Nimotuzumab 是一种针对表皮生长因子受体 EGFR 的人源化治疗性单克隆抗体。
Anti-SARS-80R mAb
T36653
Anti-SARS-80R mAb (SARS-80R) is a human IgG1 monoclonal antibody that is derived from CHO cells. Its main function is to selectively bind to the Spike (S1) prote...
Anti-SARS-CoV-2 Spike mAb (CR3022)
T36654
Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both...
Anti-MERS-2E6 mAb
T36651
Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to ...
Anti-Spike-RBD mAb
T36655
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach f...
Matuzumab
T9922
Matuzumab 是一种用于癌症治疗的人源化单克隆抗体。它对 EGFR 具有高亲和力,通常与恶性肿瘤中血管的生长有关,从而促进肿瘤的生长和存活。
Sarilumab (anti-IL-6Rα)
T35389
Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体,与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。
Anti-Spike-RBD Single Domain mAb
T36656
The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the...
Reslizumab
T12706
Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma.
meplazumab
T9931
meplazumab 是一种人源化抗 CD147 抗体,作为 COVID-19 肺炎患者的附加疗法。
Anti-MERS-3A1 mAb
T36652
Anti-MERS-3A1 mAb (MERS-3A1) is a high-affinity human monoclonal IgG1 antibody derived from CHO cells. It effectively inhibits the interaction between the MERS-C...
Spartalizumab (anti-PD-1)
T35396
Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性;MW: 145.8 KD。
Survodutide
T76559
Survodutide (BI 456906) 是一种胰高血糖素和胰高血糖素样肽 1 (GLP-1) 受体 (GLP Receptor) 双重激动剂,可降低 HbA1c16 型糖尿病的体重。
Pembrolizumab
T9908
Pembrolizumab 是一种抑制 PD-1 受体的人源化单克隆抗体,是一个 HER2 二聚化抑制剂类,它会削弱 HER2 与 HER 家族其他成员结合的能力。
Infliximab
T9921
Infliximab 是一种与 TNF-α特异性结合的嵌合单克隆 IgG1 抗体,可阻止 TNF-α与 TNFR1和 TNFR2 的相互作用,用于治疗克罗恩病和类风湿性关节炎。
Ipilimumab
T9906
Ipilimumab 是全人类单克隆抗体 IgG1κ,能够抗 CTLA-4。其中CTLA-4是一种由活化的 T 细胞产生的免疫抑制分子。
Tocilizumab
T9911
Tocilizumab 是抗人白细胞介素-6 受体 (IL-6R) 的中和抗体,能够阻碍 IL-6 与 IL-6R 的结合,进而抑制经典和反式信号。它可用于研究类风湿性关节炎,对重症 COVID-19 冠状病毒病方面的研究具有显著效果。
Secukinumab
T9930
Secukinumab 是一种完全人源化的单克隆抗 IL-17A 抗体,是一个被美国食品和药物管理局批准用于治疗中度至重度斑块型银屑病的抗体。
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