tr2

Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 via γ-glutamyl transpeptidase. PCTR2 is found in resolving mouse exudate and in both M1 and M2 macrophages differentiated from isolated human monocytes.

HTR2A antagonist 1 (Compound 15f) 是一种 HTR2A 拮抗剂，IC50 为 42.79 nM。此化合物通过激活 p53 p21 caspase 3 信号通路引起结直肠癌细胞的亚 G1 期细胞周期阻滞和凋亡，并且展示良好的肝微粒体稳定性。HTR2A antagonist 1 可用于结直肠癌研究。

Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shortens the inflammatory resolution period, and increases phagocytosis of E. coli by macrophages. When administered at a dose of 100 ng 12h post E. coli infection in a mouse model of peritonitis, MCTR2 selectively reduced the amount of the eicosanoids PGD2 and PGF2α in the exudate.

STING (WT R232) activity regulator 126 是一种具有抗菌和抗病毒作用的 STING 调节剂。

N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1657，CAS号为 2382942-32-5。

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite 是一种广泛具有抗肿瘤活性的嘌呤核苷类似物，主要用于靶向惰性淋巴系统恶性肿瘤。其抗癌机制主要通过抑制 DNA 合成和诱导细胞凋亡 (apoptosis) 来实现。

N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1623，CAS号为 145594-00-9。

N6-Bz-5’-O-DMTr-2’-O-hexadecanyl adenosine 3’-CED phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1652，CAS号为 2382942-35-8。

N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine 3’-CED phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1663，CAS号为 165381-54-4。

5’-O-DMTr-2’-OMe-5MeU-P-methyl phosphonamidite; 5’-O-DMTr-2’-O-methyl-5-methyluridine-3’-O-(P-methyl-N,N-diisopropylamino) phosphonamidite 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1620。

Levocarbastine is a second-generation H1 receptor antagonist for allergic conjunctivitis. It also acts as a potent selective antagonist for the neurotensin receptor NTS2 and is the first drug to be used to characterize different neurotensin subtypes.

5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite 为一种嘌呤核苷类似物，具有抑制 DNA 合成及诱导细胞凋亡 (apoptosis) 等抗癌机制，主要靶向惰性淋巴系统恶性肿瘤，展现出广泛的抗肿瘤活性。

5'-O-DMTr-2'-OMeU-methyl phosphonamidite is a Nucleoside Derivative - Acyclic nucleoside.

Nucleoside Derivatives - Fluoro-modified nucleosides; 2'-Modified nucleosides; Nucleoside Phosphoramidites

N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1656，CAS号为 2382942-31-4。

5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is a Nucleoside Phosphoramidite.

5'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite is a Nucleoside Phosphoramidite.

Beta-D-homoDNA-C(Bz)-phosphorami dite; N4-Benzoyl-1-[6-O-DMTr-2,3-dideoxy-4-(O-CED-phosphoramitidyl)-beta-D-erythro-hexopyranosyl)cytosine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1624。

N4-Bz-3'-O-DMTr-2'-deoxycytidine 5'-O-CE-phosphoramidite is a Nucleoside Phosphoramidite.

Nucleoside Derivatives - Anhydro-nucleosides, 5-Modified pyrimidine nucleosides; Protected nucleosides with NH2 OH group

N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1662，CAS号为 1053243-01-8。

N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU0975。

5’-O-DMTr-2’-FU-methyl   phosphonamidite 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1475。

Nucleoside phosphoramidite