thalidomide-o-c5-nh2 hydrochloride

Thalidomide-O-C5-NH2 hydrochloride is a synthetic compound consisting of a ligand-linker conjugate with E3 ligase activity. It combines a cereblon ligand based on Thalidomide and a linker commonly utilized in PROTAC technology.

Thalidomide-5-O-C5-NH2 hydrochloride是Thalidomide衍生的cereblon配体，能够招募CRBN蛋白。该化合物能透过linker与目标蛋白配体结合，用于构建PROTAC分子，如THAL-SNS-032。