tcs-ox-229

TCS-OX2-29 is a selective orexin-2 receptor antagonist (IC50 = 40 nM), which plays an important role in pain modulation.

TCS-OX2-29 是高亲和力和选择性OX2R 拮抗剂，IC50值为 40 nM，pKI 值为 7.5。它对 OX2 的选择性比 OX1 高 250 倍以上。