st 246

Tecovirimat (ST-246)是一种核心蛋白半胱氨酸蛋白酶抑制剂，可能用于治疗天花感染。Tecovirimat 是一种新型抗病毒药物，对多种正痘病毒具有有效和选择性的活性（EC50值约 10 nM）。Tecovirimat可以通过靶向病毒 p37 蛋白直系同源物来抑制正痘病毒的排出。

Tecovirimat,(ST-246, SIgA-246) is an inhibitor of p37 envelope proteins used to treat smallpox infection. Tecovirimat is an antiviral drug that is active against orthopoxviruses such as smallpox and is currently undergoing clinical trials. Its role is to

UAWJ246 is a SARS-CoV-2 Protease inhibitor (IC50 = 45 nM). UAWJ246 provides new directions for the development of Mpro inhibitors as SARS-CoV-2 antivirals.

Tecovirimat-d4 是 Tecovirimat 的氘代化合物。Tecovirimat 的 CAS 号为 816458-31-8。