Zymosan A 是一种来源于酿酒酵母(Saccharomycescerevisiae)的多糖类TLR2激动剂,可通过TLR2和Wnt信号通路上调ASCL2,促进辐射损伤后肠道干细胞(ISCs)再生,具有显著的辐射防护作用,可预防和缓解IR诱导的肠道损伤,同时能诱导免疫反应、炎症、厌食和体温升高,常用于构建腹膜炎模型。
NSC-670224 is an inhibitor of histone deacetylases-6 (HDAC6) and nuclear factor-κB (NF-κB) activation blocker. It has been shown to be toxic to Saccharomycescerevisiae at low micromolar concentrations, potentially acts via a mechanism of action related t
Puntarenine is an alkaloid of the isohomoprotoberberine family that has shown marginal activity against the dermatophytic fungus Trichophyton mentagrophytes and the yeast Saccharomycescerevisiae.
DMNB-caged-Serine is a photocaged amino acid . DMNB is a caging group which is sensitive to blue light. DMNB-caged-Serine can be incorporated into proteins in Saccharomycescerevisiae in response to the amber nonsense codon TAG, which can be helpful for controlling the chemical composition of mammalian proteins..
Tuberine, (+)- is an alkaloid isolated from Haplophyllum tuberculatum that has high antimicrobial activity against Staphylococcus aureus, Bacillus subtilis and Saccharomycescerevisiae. Tuberine, (+)- is also slightly inhibitory to Escherichia coli .
Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomycescerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A is a lipopeptide that inhibits β-glucan synthesis in yeasts. The inhibition is due to the selective blockage of glucan synthase. Aculeacin A, an amphophilic antibiotic, inhibits the biosynthesis of β−glucan by selective blockage of β(1→3) glucan synthase.