puma bh-3

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide that acts as a direct activator of Bak with a Kd of 26 nM. This peptide binds Bcl-2, localizes to mitochondria, and induces cytochrome C release.

PUMA BH3 (TFA) is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.

PUMA BH3 acetate (PUMA BH3 Free base) 是一种 p53 凋亡阳性调节因子 (PUMA) BH3 结构域多肽，可作为 Bak 的直接激活剂，Kd 为 26 nM。

PUMA BH3是一个由p53上调凋亡调节器(PUMA)的BH3域组成的肽，并激活促凋亡蛋白Bak。PUMA BH3与Bak结合（在HEPES和CHAPS缓冲液中的Kds分别为290和26 nM），诱导Bak同源寡聚化和Bak介导的膜透性增加。