Propargyl-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can be used to synthesize ADC inhibitors of Galectin-3[1].
Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].