Fasudil hydrochloride hydrate is an HCl salt of Fasudil -- a Rho-kinase (ROCK) inhibitor that has been shown to be effective in hindering the development of mature Cerebral Cavernous Malformation (CCM) lesions as well as reducing portal venous pressure in cirrhotic rats.
NLS (PKKKRKV) is a peptide derived from the 40 tumor antigen of the great ape virus (SV40 big T antigen), which is a method to enhance the nuclear portal in the research field of gene transfer.