pf03622905

PF-03622905, a potent and ATP-competitive PKC inhibitor, exhibits IC50 values of 5.6 nM, 14.5 nM, 13 nM, 37.7 nM, and 74.1 nM for PKCα, PKCβI, PKCβII, PKCγ, and PKCθ, respectively. Notably, PF-03622905 demonstrates high specificity for PKC in comparison to other protein kinases.