pd 128763

Tacrolimus anhydrous 8-epimer is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.

PD-128763是一种poly(ADP-ribose)polymerase(聚adp核糖聚合酶)的抑制剂，具有放射增敏作用，在x射线诱导的中国仓鼠V79细胞中提高了辐射诱导的细胞杀伤水平。