oxo-atp

2',3'-Dialdehyde ATP is a derivative of, and the oxidized form of, ATP. It has been found to be a specific, irreversible inhibitor of component A3 of the methylreductase system which plays a role in processing amino acids.

IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) 是一种非竞争特异性人类线粒体 RNA 聚合酶(POLRMT) 抑制剂，可引起 POLRMT 的构象变化，以剂量依赖性方式阻断底物结合和转录。它可降低脱氧核苷三磷酸水平和柠檬酸循环中间体，导致细胞氨基酸水平显著消耗，有用于线粒体转录等相关疾病的研究潜力。