midostaurin-d-5

Midostaurin-D5 is a deuterium labeled Midostaurin (T3211).

3-Hydroxy Midostaurin-D5 is a deuterium-labeled 3-Hydroxy Midostaurin (T12610L) which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 μM in culture medium and plasma).

O-Desmethyl Midostaurin-D5是O-Desmethyl Midostaurin (T12280)的氘代化合物。