mdl 1

(Z)-MDL 105519是 MDL105519 无活性的异构体。

MDL 100009 是 MDL 100151 的 S-对映体和 MDL 100907 的相反对映体，是 5-HT2A 的选择性拮抗剂。

MDL 19301 is a nonsteroidal, anti-inflammatory agent.

MDL 105519 is an effective antagonist of glycine binding to the NMDA receptor.

MDL 101146 is an orally active neutrophil elastase inhibitor.

MDL 100748 is a glycine site antagonist of NMDA receptor.

MDL-19744A is an alpha 1-adrenergic receptor antagonist and renal vasodilator.

MDL-105212A HCl is a nonpeptide NK-1 and NK-2 receptor antagonist.

MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.

MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.

Flavopiridol hydrochloride (MDL 107826A) 是一种CDK 的广谱抑制剂，与 ATP 竞争性地抑制 CDK1，CDK2 和 CDK4 的活性，IC50值分别为 30, 170, 100 nM。

MDL-100240 is a dual inhibitor of angiotensin-converting enzyme (ACE) and neprilysin with a balanced activity. MDL 100240 shows an impressive effectiveness both in preventing and in regressing hypertension-induced vascular remodeling and cardiac hypertrop

Piroximone is a phosphodiesterase (PDE) inhibitor.

Enoximone sulfoxide is a selective phosphodiesterase III (PDE3) inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. Enoximone prevents the degradation of cAMP by PDE, which prolongs signal transduction and its subsequent effects. It is used in patients with congestive heart failure.

RMI-12330A is an adenyl cyclase inhibitor.

Plomestane is a selective inhibitor of aromatization in human breast tissue and may provide a mechanism for controlling estrogen responsive processes.

RMI-18341 is a Testosterone 5 alpha reductase inhibitor.

Premazepam is a benzodiazepine derivative. It is a partial agonist of benzodiazepine receptors and was shown in 1984 to possess both anxiolytic and sedative properties in humans but was never marketed.

KAA-276 free base is a novel potent and long-lasting histamine HI-receptor antagonist with less-topical irritation, and can be topically administered by inhalation for the treatment of bronchial asthma.

VCP-746 is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling. VCP746 reduces hypertrophy in a rat neonatal cardiac myocyte model. VCP746 is a hybrid molecule consisting of an adenosine moiety linked to an adenosine A1 receptor (A1AR) allosteric modulator moiety. At the A1AR, VCP746 mediated cardioprotection in the absence of haemodynamic side effects such as bradycardia.

MDL-104168 is a macrocyclic HIV-protease inhibitor.

Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.

MDL-100173 is a dual angiotensin-converting enzyme (ACE) neutral endopeptidase (NEP) inhibitor.

MDL-102234 is an adenosine A1 receptor antagonist.