mcl1in1

Mcl1-IN-1 is a myeloid cell factor 1 inhibitor (IC50=2.4 µM).

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.

Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.

hMcl-1-IN-1 (Compound 9), 一种基于His224芳基氟磺酸酯的hMcl-1抑制剂，展示出了5.8 nM的IC50值。

Bcl-2/Mcl-1-IN-1 是一种 Bcl-2 (Ki: 4.53 μM) 和 Mcl-1 (Ki: 1.19 μM) 抑制剂。Bcl-2/Mcl-1-IN-1 能够用于研究癌症。