ldopa

L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体，具有口服活性。Levodopa 能够透过血脑屏障，并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。

L-(-)-α-Methyldopa (MK-351) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂，对 α2- adrenergic receptors 有选择性。

Methyldopa hydrate (MK-351 hydrate) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是一种 α-肾上腺素能激动剂，对α2-adrenergic receptors 有选择性。

Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).

L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts

Methyldopate HCl is an agent of antihypertensive.

Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension.

N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 μmol kg, respectively), as well as reduces homovanillic acid levels in rat striatum when administered at a dose of 80 μmol kg.1 N,N-Dipropyldopamine (0.5-16 mg kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3

N-acetyldopamine (NADA) is a catecholamine utilized by insects as a precursor for sclerotization, a process that strengthens their cuticle.

N-Methyldopamine hydrochloride （Ephinine hydrochloride) 是肾上腺髓质中肾上腺素的前体，是一种 α 和 β 激动剂，具有多巴胺的间接拟交感神经作用。

N-Arachidonyldopamine (NADA) 是一种选择性的、强效的内源性 CB1 受体激动剂 (Ki: 250 nM)。N-Arachidonyldopamine 也是一种有效的、选择性 TRPV1 激动剂，其 EC50 值 ~50 nM。

Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。

Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.

Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist. It acts as a vasodilator in vivo and does not readily cross the blood-brain barrier. Fenoldopam HCl is also an α2-adrenoceptor antagonist in vitro.

Fenoldopam hydrobromide is a Dopamine D1-receptor agonist that acts as an antihypertensive.

N-β-alanyldopamine hydrochloride (NBAD hydrochloride) 是血淋巴中多巴胺的主要衍生物。

N-Acetyldopamine dimer-2（compound 2）是一种从蝉皮黄色粉末中分离出来的N-acetyldopamine二聚体，具有抗氧化和抗炎作用。它能抑制氧化低密度脂蛋白（LDL）的氧化、ROS的生成、NO的生成以及NF-κB的活性。

N-Acetyldopamine dimer-3 (compound 11)为Aspongopus chinensis中检出的天然化合物。

3-O-Methyldopa-d3 是 3-O-Methyldopa 的氘代化合物。3-O-Methyldopa 的 CAS 号为 300-48-1。

Methyldopa-d3 是 Methyldopa 的氘代化合物。Methyldopa 的 CAS 号为 6014-30-8。

N-Acetyldopamine dimer-1是一种2-(3',4'-二羟基苯基)-1,4-苯并二氮杂环衍生物。N-Acetyldopamine dimer-1具有旋光活性，可从隐亭蝉 (Cryptotympana sp.) 的剥壳药材“Zentai”中分离而得。

N-Acetyldopamine dimers B 是由两个 N-Acetyldopamine 分子组成的二聚体。

N-Acetyldopamine dimers A (Compound (+)-2) 可以从蝉的脱落壳中分离出来，增加胶原蛋白和α-SMA表达。

5-S-Cysteinyldopamine 是多巴胺的一种硫醚代谢物，通过引发广泛的氧化应激和蛋白质聚集，导致神经性损伤，其特征为蛋白质羰基化和谷胱甘肽耗竭，并促进α-突触核蛋白（α-Syn）和ERp57蛋白的表达。5-S-Cysteinyldopamine 可用于研究神经退行性疾病，如帕金森病。