购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
筛选
已筛选:全部清除
TargetMol | Tags 通过 靶点 筛选
  • Adrenergic Receptor
    (1)
  • Cytochromes P450
    (1)
  • PPAR
    (1)
  • Others
    (2)
TargetMol | Tags 通过 货期 筛选
  • 现货
    (1)
  • 35日内发货
    (2)
  • 6-8周
    (1)
抑制剂&激动剂
细分筛选
搜索结果
TargetMol产品目录中 "gemfibrozil"的结果
筛选
搜索结果
TargetMol产品目录中 "

gemfibrozil

"的结果
  • 抑制剂&激动剂
    4
    TargetMol | Inhibitors_Agonists
  • 同位素
    1
    TargetMol | Isotope_Products
  • Gemfibrozil
    吉非罗齐, CI-719, Jezil, Decrelip, Lopid
    T141525812-30-0
    Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。
    • ¥ 115
    In stock
    规格
    数量
  • Gemfibrozil 1-O-β-glucuronide
    T1138791683-38-4
    Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil, is a potent and competitive inhibitor of P450 (CYP) isoform CYP2C8, with an IC50 of 4.07 μM.
    • ¥ 4230
    35日内发货
    规格
    数量
  • Gemfibrozil-d6
    T713061184986-45-5
    Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif ligand 2 (CCL2) in ApoE- - mice. Formulations containing gemfibrozil have been used in the treatment of high cholesterol.
    • 待估
    35日内发货
    规格
    数量
  • AH057
    T71304118499-11-9
    AH057 is a novel JAK inhibitor, effectively blocking the JAK STAT pathways by directly inhibiting JAK1 2 kinase activities, and leading to compromised cell proliferation and invasion, increasing apoptosis, arrested cell cycles, and impairing tumor progression in vitro and in vivo
    • ¥ 10600
    6-8周
    规格
    数量