faah/magl-in-3

FAAH MAGL-IN-3 (Compound 10) 是一种不可逆的脂肪酸酰胺水解酶 (FAAH)和单酰基甘油脂酶 (MAGL)双重抑制剂，能够作用于 FAAH (IC50: 179 nM) 和 MAGL (IC50: 759 nM)。FAAH MAGL-IN-3 表现出很小的 PAMPA (平行人工膜渗透性试验) 透过性。

FAAH MAGL-IN-1, also known as compound SIH 3, is a highly effective inhibitor of FAAH (fatty acid amide hydrolase) and MAGL (monoacylglycerol lipase). It exhibits IC50 values of 31 nM and 29 nM against FAAH and MAGL, respectively. This compound shows promising potential for advancing research in the field of neuropathic pain [1].