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    TargetMol | Inhibitors_Agonists
  • Eplerenone
    依普利酮, SC-66110, Epoxymexrenone, CGP 30083
    T0083107724-20-9
    Eplerenone (CGP 30083) 是一种竞争性的、选择性的、具有口服活性的醛固酮 (aldosterone) 拮抗剂，IC50=138 nM。它对孕酮，雄激素，雌激素和糖皮质激素受体的亲和力低，可用于研究高血压和心肌梗死后的心力衰竭。
    Glucocorticoid Receptor
    • ¥ 167
    现货
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  • 21-hydroxy Eplerenone
    T36129334678-67-0
    21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone . It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.
    Others
    • ¥ 5860
    35日内发货
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  • 6β-hydroxy Eplerenone
    T37064209253-80-5
    6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4. |1. Cook, C.S., Berry, L.M., Kim, D.H., et al. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: Differential metabolism by CYP3A4 and CYP3A5. Drug Metab. Dispos. 30(12), 1344-1351 (2002).
    Others
    • ¥ 7840
    35日内发货
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