elisa

MAK683 是胚胎外胚层发育 (EED) 抑制剂。在 EED Alphascreen 结合、LC-MS 和 ELISA 测定中，IC50值为 59、89 和 26 nM。

Elisartan is a non-peptide pro-drug of angiotensin II AT1 receptor antagonist HN-12206. It also shows anti-hypertension activities.

Samelisant dihydrochloride (SUVN-G3031) is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating disorders, and pain.

Samelisant (SUVN-G3031) 是 H3 受体的特异性反向激动剂，对人和大鼠的 Kis 分别为 8.7 nM 和 9.8 nM。 Samelisant 具有抗猝倒作用，可用于关于发作性睡病的研究。

LF3 是一种典型 Wnt 信号传导的特异性抑制剂，通过破坏 β-catenin 和 TCF4 之间的相互作用（IC50 < 2 μM）

MAK683 hydrochloride胚胎外胚层发育 (EED) 抑制剂，也是一种高效的 PRC2 抑制剂，可阻断癌细胞增殖（IC50=1.014），在EED Alphascreen， ELISA 和 LC-MS 试验中测得的IC50 值分别为 59，26，89 nM。

Signal enhancer for use in western blotting, dot blotting and ELISA

CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing BxPC-3 pancreatic cancer cells when used at a concentration of 20 μM. CAY10760 (20 μM) decreases proliferation of BxPC-3, as well as mutantBRCA2-expressing Capan-1, cancer cells when used alone or in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib . 1.Bagnolini, G., Milano, D., Manerba, M., et al.Synthetic lethality in pancreatic cancer: Discovery of a new RAD51-BRCA2 small molecule disruptor that inhibits homologous recombination and synergizes with olaparibJ. Med. Chem.63(5)2588-2619(2020)

C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal C2BBe1 cells.

R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI). It inhibits the expression of intercellular adhesion molecule-1 (ICAM-1) induced by TNF-α and IL-1β with EC50 values of 2.45 and 3.79 μM, respectively, in an ELISA using A549 lung epithelial cells.{|Gururaja2007|} It also disrupts the interaction of the TNF-αRI with receptor interacting protein 1 (RIP1) and TNF-αR-associated death domain protein (TRADD), preventing internalization of the receptor complex.

TDRL-X80 是一种色素性干皮症蛋白 (XPA) 的有效抑制剂。TDRL-X80 能够抑制 XPA 的 DNA 结合活性。TDRL-X80 能够作用于单、双和顺铂损伤的 DNA，在荧光偏振 (FP) 分析中的 IC50 值为 18、20 和 29 μM，而 ELISA 分析中的 IC50为 21、39 和 28。

Blapsin B is a potent 14-3-3 inhibitor. Blapsin B is a naturally occurring compound isolated from the ethanol extract of the stink beetle, Blaps japanensis. Blapsin B potently inhibited 14-3-3 protein-protein interactions (PPIs) with IC(50) value of 10.0 μM as determined by an ELISA assay, and 2.5 μM in an FP assay, respectively. Blapsin B represent the first example of natural small-molecule 14-3-3 inhibitors.

VLVNTFCDSCIPKTYWNLGY TFA，作为M3毒蕈碱受体（M3R）的抗原肽，适用于ELISA实验。

Anti-Mouse IFNAR1 Antibody (MAR1-5A3) 是一种中和 IFNAR1 的抗体，可与IFNAR1结合并阻断信号传导，可用于蛋白质印迹、免疫组化、流式细胞术、免疫细胞化学和 ELISA。

PHD-IN-1（compound 80）作为PHD2的抑制剂，显示出 IC50 ≤5 nM 的高效活性。在Caco2-HIFla-HiBiT-clone-1和Hep3B细胞系中进行的EPO Elisa实验中，其EC50值均为2.5 μM。

GluR23Y是一种具有生物活性的肽，应用于ELISA细胞表面测定，专用于监测培养的海马神经元内AMPA受体在胰岛素刺激下的内吞情况。该肽能够阻止由胰岛素引起的AMPA受体数量的下降。通过将GluR23Y与HIV-1的膜转导结构域融合，实现对神经元的传递，从而有效抑制了胰岛素诱导的效应。

HMBPP analog 1 (6e) 为 Trifluoromethyl 的类似物,其在HMBPPELISA 反应中表现出强抑制和弱激活的双重性能.

Anti-DM1 antibody (14E3) (Rabbit mAb) 是源自兔子的 IgG 抗体，专门靶向 DM1，可在无物种差异影响的情况下应用于ELISA实验。

Anti-mouse OX40 CD134 抗体可用于ELISA, Flow cytometry等相关的研究。

Anti-mouse CTLA-4 CD152 Nanobody 抗体可用于Neutralisation,ELISA, Flow cytometry, X-ray crystallography等相关的研究。

Anti-CD207 抗体可用于ELISA, Flow cytometry等相关的研究，同型对照亚型是mouse IgG2b。

Anti-CD47 (h4C1) 抗体可用于Block, ELISA, FC等相关的研究。

Acetylated-BSA是一种具有已知结构的多肽，具有强抗原性，用于验证实验方法的准确性和可靠性。Ac-BSA 可在 ELISA 或 WB 实验中作为阳性对照，特别是在乙酰化赖氨酸单克隆或多克隆抗体实验中应用。此外，Bovine Serum Albumin, Acetylated 有助于提高低浓度 PLGA 的包封效率，而 PLGA 是一种生物相容性、降解性和控释特性的药物递送聚合物。

o-Dianisidine盐酸盐是一种用于ELISA检测的比色过氧化物酶底物。