dimaprit

Dimaprit dihydrochloride 是组胺H2受体的一种选择性激动剂，可刺激胃酸的分泌。它还抑制nNOS，IC50值为 49 μM。

Nordimaprit dihydrochloride is a metabolite of Dimaprit -- a histamine analog and selective H2 histamine receptor agonist.

Nordimaprit is effective agonist in the inhibition of lymphocyte activation.

QZN34 is a PqsR inhibitor which prevents S. aureus biofilm formation, severely damaged established S. aureus biofilms, and perturbed P. aeruginosa biofilm development. The mechanism of action of QZN 34 toward Gram-positive bacteria is shown to involve membrane perturbation and dissipation of transmembrane potential.