compound 48/80 trihydrochloride

Compound 48 80 trihydrochloride (C48 80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48 80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48 80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。

Compound 48/80, also known as Poly-p-methoxyphenethylmethylamine, is a commonly utilized mast cell activator in animal and tissue models. This compound exerts its effect by stimulating trimeric G-proteins at the mast cell membrane, triggering degranulation through both phospholipase C and D pathways.