bumetanide d5

Bumetanide D5 is a deuterium-labeled Bumetanide. Bumetanide is a Na+-K+-Cl- (NKCC1) inhibitor (IC50s: 0.68 and 4.0 μM for hNKCC1A and hNKCC2A).

Bumetanide (Standard) 是 Bumetanide 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Bumetanide (PF 1593) 是一种高效的利尿剂，是 Na+-K+-Cl+协同转运蛋白 (NKCC) 的阻断剂。它是选择性的NKCC1和NKCC2抑制剂，对 hNKCC1A 和 hNKCC2A 作用的IC50值分别为 0.68 和 4.0 μM。

Bumetanide sodium is a potent loop diuretic that acts as a blocker for the sodium-potassium-chloride cotransporter (NKCC). It selectively inhibits NKCC1 and NKCC2, with IC50 values of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively [1] [2].