atrial natriuretic factor tfa

Atrial Natriuretic Peptide (ANP) (1-28), rat (TFA), is the primary circulating form of ANP in rats and significantly inhibits Ang II-stimulated secretion of endothelin-1.

Atrial natriuretic factor (1-28) (human, porcine) TFA 通过增强钠和尿液的排泄来发挥降血压的作用。此外，它通过抑制促阿片黑素皮质素 (POMC) 的表达，抑制垂体中促肾上腺皮质激素 (ACTH) 和 β-内啡肽的释放。Atrial natriuretic factor (1-28) (human, porcine) TFA 还在 RMIC 细胞中增加 cGMP 水平，IC50为 1.2 nM。