ammtx-3

KV4 channel blocker. Blocks A-type K+ current (ISA) in mouse cerebellar granule neurons. The accessory dipeptidyl peptidase-like proteins (DPP) 6 and 10 are required for blockade.

AmmTX3 TFA为来源于蝎子Androctonus mauretanicus毒液的肽类毒素，特异性拮抗Kv4通道，有效抑制A型K+电流（Ki: 131 nM）。