| Cat. No. | Product Name | Target | Signaling Pathways |
|---|---|---|---|
| T41085 |
UK122
UK122 |
||
| UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). Functioning as a 4-oxazolidinone analogue, UK122 is an anticancer agent that effectively inhibits cancer cell migration and invasion. | |||
| T29051 |
UK-122 TFA salt
UK-122,UK122 TFA salt,UK122,UK 122,uPA Inhibitor II,K122 trifloroacetic acid |
||
| UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migratio | |||
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