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Cat. No. |
Product Name |
Target |
Signaling Pathways |
T17164
|
Trimetrexate
|
Others |
Others |
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Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase. |
T63985
|
Trimetrexate glucuronate
|
|
|
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Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist that inhibits dihydrofolate reductase, which in turn blocks the synthesis of purine nucleotides and thymidylic acid, affecting DNA and RNA synthesis and exhibiting potential anti-tumour effects. |