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抑制剂 & 化合物

1728

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T26188 Setin-1

Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.

化合物

Setin-1
Cat.No: T26188
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus-Insect Cells
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...

Human HEK293
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

Angiopoietin-2,AGPT2,angiopoietin 2,ANG2

Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization. ANG-2 mod...
TMPY-01298 CADM1 Protein, Human, Recombinant (His)

Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-

Human HEK293
Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular domain of IGSF4 and mediate homophilic or heterophilic interactions independently of Ca2+. The cytoplasmic domain of IGSF4 contains the binding motifs that connect to actin fibers. Since IGSF4 has been characterized by several independent research groups, this molecule is called...
TMPY-04779 BTN3A2 Protein, Human, Recombinant (His)

BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...

Human HEK293
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted...
TMPY-03363 C-Reactive Protein Protein, Human, Recombinant

C-Reactive Protein,C-reactive protein, pentraxin-related,PTX...

Human HEK293
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monit...
TMPY-05275 CD79B Protein, Human, Recombinant (His)

B29,IGB,CD79b molecule, immunoglobulin-associated beta,AGM6,...

Human HEK293
TMPY-02512 Alpha-Synuclein Protein, Human, Recombinant

PD1,α-Synuclein,PARK4,synuclein, α (non A4 componen...

Human E. coli
Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the...
TMPY-05354 CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD28 molecule,Tp44

Human HEK293
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc)

1810061I13Rik,Clec2,C-ty...

Mouse HEK293
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and...
TMPY-04824 CTLA-4 Protein, Human, Recombinant

CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD4,cytotoxic T...

Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role i...
TMPY-00986 IL-34 Protein, Mouse, Recombinant (His)

interleukin 34,2010004A03Rik,AI593503

Mouse HEK293
IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colon...
TMPY-03273 IL-18 Protein, Mouse, Recombinant

interleukin 18,白细胞介素,白介素,Il-18,Igif

Mouse E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi...
TMPY-02412 ENO1 Protein, Human, Recombinant (His)

PPH,NNE,enolase 1, (alpha),ENO1L1...

Human E. coli
The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make ...
TMPY-01055 IL-4R Protein, Human, Recombinant (His)

interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His)

HPT-1,cadherin 17, LI cadherin (liver-inte...

Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-01834 CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)

CD16,Fc receptor, IgG, low affinity III

Mouse HEK293
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as...
TMPY-01608 Decorin Protein, Human, Recombinant (His)

PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII

Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role...
TMPY-00843 IL-25/IL17E Protein, Human, Recombinant (hFc)

interleukin 25,IL17E

Human HEK293
Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–produ...
TMPY-05277 IL-4R Protein, Human, Recombinant (hFc)

IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-04810 CD47 Protein, Mouse, Recombinant (His)

AA407862,CD47 molecule,AW108519,91

Mouse HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...

Human HEK293
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)

interleukin 11 receptor subunit alpha,hCG_...

Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increas...
TMPY-03256 NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)

KLR,killer cell lectin-like receptor subfamily K, member

Human Baculovirus-Insect Cells
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim...
TMPY-05579 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

PRR1,ED4,PVRR,nectin-1,OFC7,SK-12...

Human HEK293
Poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin-1; CD111), also known as PVRL1 is a cell adhesion molecule belonging to the immunoglobulin superfamily that can bind to virion glycoprotein D (gD) to mediate entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV). CD111/Nectin-1/PVRL1 colocalizes with E-cadherin at adherens junctions in epithelial cells. The disruption of cell junctions can result in the redistribution of nectin-1. To determine whether disruption of ...
TMPY-00939 Thrombopoietin Protein, Mouse, Recombinant (His)

thrombopoietin,Mpllg,Tpo,Mgdf,Ml

Mouse HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin...
TMPY-01968 CD32A Protein, Human, Recombinant (167 His, His)

IGFR2,CDw32,CD32,CD32A,FCGR2,Fc gamma RIIA,FcGR,Fc γ RIIA,FC...

Human HEK293
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)

angiopoietin 1,AGPT,AGP1,ANG1

Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures...
TMPY-03762 E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)

cadherin 1, type 1, E-cadherin (epithelial...

Human HEK293
Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is a calcium-dependent cell adhesion molecule the intact function of which is crucial for the establishment and maintenance of epithelial tissue polarity and structural integrity. Mutations in CDH1 occur in diffuse type gastric cancer, lo...
TMPY-01431 L1CAM Protein, Human, Recombinant (His)

N-CAM-L1,MASA,HSAS,L1 cell adhesion molecu...

Human HEK293
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif ...
TMPY-01701 IL-12RB1 Protein, Human, Recombinant (His)

interleukin 12 receptor, β1,IL12R...

Human HEK293
Interleukin 12 receptor, beta 1 is also known as IL-12 receptor beta component, IL-12R subunit beta-1, and CD212 antigen (CD212). IL12RB1(CD212) is a subunit of the interleukin 12 receptor. IL12RB1(CD212) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukin 12 (IL12) with a low affinity and is thought to be a part of the IL12 receptor complex. IL12RB1(CD212) forms a disulfide-linked oligomer, which is required for its IL12 bind...
TMPY-01907 VSIG4 Protein, Human, Recombinant (His)

Z39IG,CRIg,V-set and immunoglobulin domain containing 4

Human HEK293
VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPY-02115 R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

CRISTIN1,THSD2,R-spondin 3,PWTSR

Human HEK293
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s...
TMPY-04793 IL-35 Protein, Human, Recombinant (Flag & His)

NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NFSK,IL-

Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T...
TMPY-06076 LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like...

Human HEK293
LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophag...
TMPY-02105 SCF Protein, Mouse, Recombinant (His)

Gb,Kitlg,SF,Clo,Mgf,SLF,Sl,KIT ligand,SCF,Con

Mouse Baculovirus-Insect Cells
Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in ...
TMPY-00828 Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)

MPS2,IDS,SIDS,iduronate 2-sulfatase

Human HEK293
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an...
TMPY-00991 LIFR Protein, Human, Recombinant (His)

STWS,CD118,SJS2,LIF-R,leukemia inhibitory ...

Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus affects the differentiation, proliferation, and survival of a wide variety of cells in the adult and the embryo. Besides LIF, LIFR can also bind to and activate CNTF (ciliary neurotrophic factor) and CLC (Cardiotrophin Like Cytokine). Evidence showed that in the retina, LIFR activat...
TMPY-03630 MZB1/PERP1 Protein, Human, Recombinant (His)

MEDA-7,marginal zone B and B1 cell-specific protein...

Human HEK293
MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expressi...
TMPY-05566 Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)

CD22 molecule,SIGLEC-2,SIGLEC2

Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. In addition to its potential role as a mediator of intercellular interactions, signal transduction through CD22 can activate B cells and modulate antigen receptor signaling in vitro. ...
TMPY-06051 SIRP alpha Protein, Human, Recombinant (hFc)

signal-regulatory protein alpha,SIRP alpha,PTPNS1,P...

Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antigen-like family member A, SIRPA and CD172a, is a single-pass type I membrane protein which contains two Ig-like C1-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIRPA is ubiquitously expressed. It is highly expressed in brain and detected ...
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His)

CD123,interleukin 3 receptor, alpha (low affinity),...

Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subfamily. The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. The WSXWS motif of IL3RA appears to be necessary for prop...
TMPY-00908 Renin Protein, Human, Recombinant (His)

REN,renin,FLJ10761,HNFJ2

Human HEK293
Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angio...
TMPY-04956 HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p1...

Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-04483 IRAK4 Protein, Human, Recombinant (His)

IPD1,NY-REN-64,REN64,interleukin-1 recepto...

Human Baculovirus-Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ...
TMPY-01139 PDGFRA Protein, Human, Recombinant (His)

PDGFR-2,CD140A,RHEPDGFRA,platelet-derived growth fa...

Human HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfamily of receptor tyrosine kinase (RTKs) with the similar structure characteristics of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. PDGFRA is expressed in oligodendrocyte progenitor cells and mesothelial cell...
TMPY-04782 LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His)

LIR6,leukocyte immunoglobulin like receptor A1,LIR-...

Human HEK293
TMPY-05030 PCDH7 Protein, Human, Recombinant (His)

BHPCDH

Human Baculovirus-Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC).
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重组蛋白

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03745
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00664
Species: Human
Expression System: HEK293
CADM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01298
Species: Human
Expression System: HEK293
BTN3A2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04779
Species: Human
Expression System: HEK293
C-Reactive Protein Protein, Human, Recombinant
Cat.No: TMPY-03363
Species: Human
Expression System: HEK293
CD79B Protein, Human, Recombinant (His)
Cat.No: TMPY-05275
Species: Human
Expression System: HEK293
Alpha-Synuclein Protein, Human, Recombinant
Cat.No: TMPY-02512
Species: Human
Expression System: E. coli
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05354
Species: Human
Expression System: HEK293
CLEC-2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00586
Species: Mouse
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant
Cat.No: TMPY-04824
Species: Human
Expression System: HEK293
IL-34 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00986
Species: Mouse
Expression System: HEK293
IL-18 Protein, Mouse, Recombinant
Cat.No: TMPY-03273
Species: Mouse
Expression System: E. coli
ENO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02412
Species: Human
Expression System: E. coli
IL-4R Protein, Human, Recombinant (His)
Cat.No: TMPY-01055
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPY-01912
Species: Human
Expression System: HEK293
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
Cat.No: TMPY-01834
Species: Mouse
Expression System: HEK293
Decorin Protein, Human, Recombinant (His)
Cat.No: TMPY-01608
Species: Human
Expression System: HEK293
IL-25/IL17E Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00843
Species: Human
Expression System: HEK293
IL-4R Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05277
Species: Human
Expression System: HEK293
CD47 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04810
Species: Mouse
Expression System: HEK293
FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
Cat.No: TMPY-01462
Species: Human
Expression System: HEK293
NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)
Cat.No: TMPY-03256
Species: Human
Expression System: Baculovirus-Insect Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05579
Species: Human
Expression System: HEK293
Thrombopoietin Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00939
Species: Mouse
Expression System: HEK293
CD32A Protein, Human, Recombinant (167 His, His)
Cat.No: TMPY-01968
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05435
Species: Human
Expression System: HEK293
E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03762
Species: Human
Expression System: HEK293
L1CAM Protein, Human, Recombinant (His)
Cat.No: TMPY-01431
Species: Human
Expression System: HEK293
IL-12RB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01701
Species: Human
Expression System: HEK293
VSIG4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01907
Species: Human
Expression System: HEK293
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
Cat.No: TMPY-02115
Species: Human
Expression System: HEK293
IL-35 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-04793
Species: Human
Expression System: HEK293
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06076
Species: Human
Expression System: HEK293
SCF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02105
Species: Mouse
Expression System: Baculovirus-Insect Cells
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
Cat.No: TMPY-00828
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (His)
Cat.No: TMPY-00991
Species: Human
Expression System: HEK293
MZB1/PERP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03630
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
Cat.No: TMPY-05566
Species: Human
Expression System: HEK293
SIRP alpha Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06051
Species: Human
Expression System: HEK293
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
Cat.No: TMPY-01410
Species: Human
Expression System: HEK293
Renin Protein, Human, Recombinant (His)
Cat.No: TMPY-00908
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04956
Species: Human
Expression System: HEK293
IRAK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04483
Species: Human
Expression System: Baculovirus-Insect Cells
PDGFRA Protein, Human, Recombinant (His)
Cat.No: TMPY-01139
Species: Human
Expression System: HEK293
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His)
Cat.No: TMPY-04782
Species: Human
Expression System: HEK293
PCDH7 Protein, Human, Recombinant (His)
Cat.No: TMPY-05030
Species: Human
Expression System: Baculovirus-Insect Cells
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