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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22377 |
NIBR-17
|
PI3K | PI3K/Akt/mTOR signaling |
NIBR-17 是一种泛 I 类 PI3K 抑制剂。 NIBR-17 抑制 PI3KKα、PI3KKβ、PI3KKγ 和 PI3KKδ,IC50 分别为 1 nM、9.2 nM、9 nM 和 20 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00423 |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FGFR2 α(IIIb),CD332,fibroblas... |
Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. It is required for normal embryonic patterning, trophoblast function, limb bud development, lung mor... | |||
TMPK-00401 |
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD1,KGFR,TK14,FGFR2 α (IIIb),... |
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. | |||
TMPY-03389 |
FGFR2 Protein, Mouse, Recombinant (His)
svs,Fgfr-7,fibroblast growth factor receptor 2,KGFRTr,Bek,AW... |
Mouse | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. It is required for normal embryonic patterning, trophoblast function, limb bud development, lung mor... | |||
TMPK-00847 |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 β (IIIb),KGFR,BEK,CD332,K-sam,FGFR-2,Keratinocyte grow... |
Mouse | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors... |