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  • Imexon
    亚美克松, BM 06002
    T1556659643-91-3
    Imexon is an iminopyrrolidone aziridine. It has anti-cancer activity.
    • 待询
    8-10周
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  • AMP423
    T69821219501-57-2
    AMP423 is a naphthyl derivative of 2-cyanoaziridine-1-carboxamide with structural similarity to the pro-oxidant anti-tumor agent imexon. AMP423 was active in SCID mice bearing 8226 S myeloma and SU-DHL-6 B-cell lymphoma tumors, with a median tumor growth delay (T-C) of 21 days (P = 0.0002) and 5 days (P = 0.004), respectively, and a median tumor growth inhibition (T C) of 33.3% (P = 0.03) and 82% (P = 0.01), respectively. In non-tumor-bearing mice, AMP423 was not myelosuppressive.
    • ¥ 10600
    6-8周
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