| Cat. No. | Product Name | Target | Signaling Pathways |
|---|---|---|---|
| T15566 |
Imexon
BM 06002,亚美克松 |
Others | Others |
| Imexon is an iminopyrrolidone aziridine. It has anti-cancer activity. | |||
| T69821 | AMP423 | ||
| AMP423 is a naphthyl derivative of 2-cyanoaziridine-1-carboxamide with structural similarity to the pro-oxidant anti-tumor agent imexon. AMP423 was active in SCID mice bearing 8226/S myeloma and SU-DHL-6 B-cell lymphoma tumors, with a median tumor growth delay (T-C) of 21 days (P = 0.0002) and 5 days (P = 0.004), respectively, and a median tumor growth inhibition (T/C) of 33.3% (P = 0.03) and 82% (P = 0.01), respectively. In non-tumor-bearing mice, AMP423 was not myelosuppressive. | |||
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