GDP-​α-D-​mannose disodium

GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of

GDP-D-mannose disodium 包含 GDP-α-D-mannose 和 GDP-β-D-mannose两种组分。其中 GDP-α-D-mannose可作为甘露糖基转移酶的供体底物，同时也是 GDP-β-L - 岩藻糖的合成前体。GDP-α-D-mannose对 GTP 表现出竞争性抑制作用，Ki 值为 14.7 μM；对mannose-1-P则呈非竞争性抑制，Ki 值为 115 μM 。