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Search Results for "GDC-0276"
Targets Recommended: Others

1

抑制剂 & 化合物

2

化合物库

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Cat. No. Product Name
L1110 微管靶向化合物库

80 compounds
A unique collection of 80 microtubule-targeted compounds can be used in HTS and HCS;
L2550 谷氨酰胺代谢化合物库

580 compounds
A unique collection of 580 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and cancer;

化合物库

微管靶向化合物库
L1110
Compounds: 80
谷氨酰胺代谢化合物库
L2550
Compounds: 580
Cat. No. Product Name Target Signaling Pathways
T11377 GDC-0276

Others Others
GDC-0276 has the potential for the treatment of pain and to address shortcomings of existing pain medications, such as addiction and off-target side effects. GDC-0276 is a potent, selective, reversible and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM. GDC-0276 is well tolerated and exhibits a good pharmacokinetic profile.

化合物

GDC-0276
T11377
synonym:
Target: Others