Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11377 |
GDC-0276
|
Others | Others |
GDC-0276, a potent, selective, reversible, and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM, offers potential for pain treatment while overcoming limitations associated with current pain medications, including addiction and off-target side effects. It is well tolerated and demonstrates a favorable pharmacokinetic profile. |