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Search Results for " arap "

Targets Recommended: Phospholipase

7

抑制剂 & 化合物

2

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6109	Darapladib 达拉地,SB-480848	Phospholipase	Metabolism
	Darapladib (SB-480848) 是脂蛋白相关磷脂酶A2 (Lp-PLA2) 抑制剂，IC50=0.25 nM。
T31204	Darapladib-impurity	Others	Others
	Darapladib-impurity 是 Darapladib 的杂质。Darapladib 对脂蛋白相关磷脂酶 A2 (Lp-PLA2)有抑制作用。
T24594	Paraprost
	Paraprost consists of 1-glutamic acid, alanine, and glycine. It was used in prostate hypertrophy drug therapy.
T62218	Parapenzolate bromide
	Parapenzolate bromide 是一种口服具有活力的 mAChR 拮抗剂。Parapenzolate bromide 是一种抗胆碱能剂，也是一种解痉挛剂。
T34751	Usmarapride free base SUVN-D4010,SUVN-D 4010,SUVN-D-1208045,SUVN-1004028,SUVN D4010,SUVN-D1003019
	SUVN-D4010 is an effective, selective, brain penetrant, and orally active agonist of 5-HT4 receptor partially used to treat Alzheimer's disease and other dementia-related cognitive dysfunction.
T63069	Usmarapride
	Usmarapride (SUVN-D4010) 是一种选择性的、口服具有活力的、有效的、具有血脑屏障通透性的 5-HT4 受体部分激动剂，其 EC50 值为 44 nM。Usmarapride (SUVN-D4010) 能够用于研究阿尔茨海默病相关认知缺陷。
T70473	Parapenzolate Free Base
	Parapenzolate Free Base is a safe and effective anticholinergic drug possessing antisecretory and antimotility properties and prolonged duration of action. Clinical investigation has shown that after an oral dose of the drug there was inhibition of both basal and histamine-stimulated acid outputs.

化合物

Cat.No: T6109

Synonym: 达拉地,SB-480848

Target: Phospholipase

Darapladib-impurity

Cat.No: T31204

Target: Others

Cat.No: T24594

Parapenzolate bromide

Cat.No: T62218

Usmarapride free base

Cat.No: T34751

Synonym: SUVN-D4010,SUVN-D 4010,SUVN-D-1208045,SUVN-1004028,SUVN D4010,SUVN-D1003019

Cat.No: T63069

Parapenzolate Free Base

Cat.No: T70473

Cat. No.	Product Name	Target	Signaling Pathways
TN5636	Caraphenol A
	Caraphenol A是一种天然产物，属于豆科锦鸡儿属，其产品编号为 TN5636，CAS号为 354553-35-8。Caraphenol A可用作对照参考。
TN4269	Isocarapanaubine	Others	Others
	Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.

天然产物

Cat.No: TN5636

Isocarapanaubine

Cat.No: TN4269

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00024	Midkine Protein, Human, Recombinant (His & Avi), Biotinylated MK1,MK,MDK,NEGF2,MKARAP,MEK,ARAP	Human	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPK-00023	Midkine Protein, Human, Recombinant (His & Avi) MDK,MEK,MK1,MKARAP,ARAP,MK,NEGF2	Human	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu...
TMPK-00812	Midkine Protein, Mouse, Recombinant (His) MK1,ARAP,MKARAP,MEK,MK,NEGF2,MDK	Mouse	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mo...
TMPY-02172	Midkine Protein, Human, Recombinant midkine (neurite growth-promoting factor 2),NEGF2,MK,ARA...	Human	Baculovirus Insect Cells
	Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angio...
TMPJ-00015	GABARAP Protein, Human, Recombinant (His & hFc) GABA(A) Receptor-Associated Protein,HCG1987397 Isoform CRA_b...	Human	E. coli
	GABARAP Protein, Human, Recombinant (His & hFc) is expressed in E. coli expression system with N-6xHis and C-Fc tag. The predicted molecular weight is 50 KDa and the accession number is Q6IAW1.
TMPY-02117	Marapsin Protein, Human, Recombinant (His) UNQ1884/PRO4327,protease, serine 27,CAPH2,MPN	Human	HEK293 Cells
	The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most stro...
TMPY-03268	GABARAPL1 Protein, Human, Recombinant (His) GEC1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GABA(A) receptor-assoc...	Human	E. coli
	ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient deple...
TMPY-00587	GABARAP Protein, Human, Recombinant (His & MBP) GABARAP-a,GABA(A) receptor-associated protein,ATG8A...	Human	E. coli
	The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential...
TMPJ-00016	GABARAP Protein, Human, Recombinant (GST) GABARAP,GABA(A) Receptor-Associated Protein,GAB...	Human	E. coli
	GABARAP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37 KDa and the accession number is Q6IAW1.
TMPH-00062	Icarapin Protein, Apis mellifera carnica, Recombinant (His & Myc)	Apis mellifera carnica	E. coli
	Icarapin Protein, Apis mellifera carnica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.7 kDa and the accession number is Q5EF78.
TMPY-03461	GABARAPL2 Protein, Human, Recombinant (His) GATE16,ATG8,ATG8C,GEF-2,GATE-16,GEF2,GABA(A) receptor-associ...	Human	E. coli
	GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.

重组蛋白

Midkine Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00024

Species: Human

Expression System: E. coli

Midkine Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00023

Species: Human

Expression System: E. coli

Midkine Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00812

Species: Mouse

Expression System: E. coli

Midkine Protein, Human, Recombinant

Cat.No: TMPY-02172

Species: Human

Expression System: Baculovirus Insect Cells

GABARAP Protein, Human, Recombinant (His & hFc)

Cat.No: TMPJ-00015

Species: Human

Expression System: E. coli

Marapsin Protein, Human, Recombinant (His)

Cat.No: TMPY-02117

Species: Human

Expression System: HEK293 Cells

GABARAPL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03268

Species: Human

Expression System: E. coli

GABARAP Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-00587

Species: Human

Expression System: E. coli

GABARAP Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00016

Species: Human

Expression System: E. coli

Icarapin Protein, Apis mellifera carnica, Recombinant (His & Myc)

Cat.No: TMPH-00062

Species: Apis mellifera carnica

Expression System: E. coli

GABARAPL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03461

Species: Human

Expression System: E. coli

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