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Targets Recommended: Prostaglandin Receptor

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Cat. No. Product Name Target Signaling Pathways
T7652 AM211

AM211 free acid

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
AM211 (AM211 free acid) 是可口服的选择性前列腺素受体拮抗剂,对人、小鼠、豚鼠和大鼠的 DP2 的IC50值分别为 4.9、7.8、4.9 和 10.4 nM。
T71088 AM-211 sodium

Others Others
AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay.

化合物

AM211
Cat.No: T7652
Synonym: AM211 free acid
Target: Prostaglandin Receptor
AM-211 sodium
Cat.No: T71088
Synonym:
Target: Others
TargetMol Loading
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