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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3237 | 7-Isopentenyloxy-gamma-fagarine | Others | Others |
7-Isopentenyloxy-gamma-fagarine has highly cytotoxicity against the MCF-7and Jurkat cell line. It has been used as a precursor for the chemical asymmetric synthesis of the enantiopure alkaloids: evoxine, anhydroevoxine and evodine. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06036 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob... |
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc... | |||
TMPK-00828 |
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin-1,H23AG,PEM,CA 15... |
Human | HEK293 |
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. | |||
TMPK-00392 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1 |
Human | HEK293 |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. | |||
TMPK-00394 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1 |
Human | HEK293 |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. | |||
TMPK-01371 |
IGFBP-7 Protein, Human, Recombinant (hFc)
RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7 |
Human | HEK293 |
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. | |||
TMPY-06035 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR,HBGFR,FLT-2,FGFB... |
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc... | |||
TMPK-00393 |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 α,FGFR1 alpha,FGF R1a,FGFR1 α (IIIc) |
Human | HEK293 |
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cel... | |||
TMPK-00395 |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGF R1a,FGFR1 α,FGFR1 alpha,FGFR1 α (IIIc) |
Human | HEK293 |
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cel... |