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Targets Recommended: Endothelin Receptor

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Cat. No. Product Name Target Signaling Pathways
TQ0270 Atrasentan hydrochloride

(+)-A 127722 hydrochloride,ABT-627 hydrochloride,盐酸阿曲生坦,A-147627 hydrochloride

Endothelin Receptor GPCR/G Protein
Atrasentan hydrochloride (ABT-627 hydrochloride) 是内皮素 A 受体选择性拮抗剂,抑制内皮素 A 受体活性的IC50为 0.0551 nM。
TQ0259 Atrasentan

A-147627,(+)-A 127722,阿曲生坦,ABT-627

Endothelin Receptor GPCR/G Protein
Atrasentan (ABT-627) 是内皮素受体 (endothelin receptor) 拮抗剂,能够抑制 ETA 的活性(IC50:0.0551 nM)。
T70198 Atrasentan sodium

Others Others
Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.

化合物

Atrasentan hydrochloride
Cat.No: TQ0270
Synonym: (+)-A 127722 hydrochloride,ABT-627 hydrochloride,盐酸阿曲生坦,A-147627 hydrochloride
Target: Endothelin Receptor
Atrasentan
Cat.No: TQ0259
Synonym: A-147627,(+)-A 127722,阿曲生坦,ABT-627
Target: Endothelin Receptor
Atrasentan sodium
Cat.No: T70198
Synonym:
Target: Others
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