β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50)
Lancifodilactone F exerts minimal cytotoxicity against C8166 cells (CC50 > 200 microg mL) and shows anti-HIV activity with EC50 = 20.69 + - 3.31 microg mL and a selectivity index > 6.62.
Chamigrenol is a promising candidate for the development of potent Na+/K+ ATPase inhibitors and antimicrobial agents. It inhibited the activities of Na+/K+-ATPase, with the IC50 value of 15.9 ± 0.54 μg/mL.