Odorine and odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. (+)-Odorinol exhibits strong antiviral activity against Ranikhet disease virus (RVD) in chick embryo.
Odorine has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis. It was found to inhibit the growth of the vinblastine-resistant KB cells by enhancing the anticancer activity of vinblastine.
Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng. Dipterocarpol A shows moderate acetylcholinesterase inhibitory activity with the IC50 value of 8.28 uM.
Eichlerialactone and ethyl eichlerianoate show antimycobacterial activity against mycobacterium tuberculosis H37Ra, with minimum inhibitory concentration in the range of 25-50ug/mL; eichlerialactone exhibits good antibacterial activity against both the Gr
Dammarenediol II 可能通过有效抑制血管内皮生长因子(VEGF)诱导的细胞内活性氧生成、应力纤维形成及血管内皮钙黏蛋白破坏,从而对糖尿病微血管并发症(包括糖尿病视网膜病变)发挥保护作用。Dammarenediol II 能够维持内皮完整性,Dammarenediol II 这个重要药用价值的三萜类化合物还可在烟草中实现异源生物合成,其生物合成过程使植物获得抗病毒防御能力,凸显了其在代谢性疾病研究、血管生物学及植物生物制造策略中的研究价值。
Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. It also has insecticidal activity.
5,6-Desmethylenedioxy-5-methoxyaglalactone is cytotoxic to small cell lung cancer (NCI-H187) cell line. It has antimycobacterial activity against Mycobacterium tuberculosis H(37)Ra.
Aglinin A displays moderate cytotoxicity against all the three cancer cell lines((NCI-H187), epidermoid carcinoma (KB) and breast cancer (BC) cell lines).
Rocaglaol is a potent anticancer drug that induces apoptosis of LNCaP cells through the mitochondrial pathway and its G2/M-phase cell cycle arrest is associated with the down-regulation of Cdc25C and the dephosphorylation of Cdc2. Rocaglaol can reduce tis