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  • Butein
    T6427487-52-5
    Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂,也是蛋白酪氨酸激酶抑制剂,还是一种SIRT1激活剂。它通过 AKT 和 ERK p38 MAPK 通路,靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
    • ¥ 296
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    TargetMol | Inhibitor Hot
    TargetMol | Citations 客户已引用
  • Isolicoflavonol
    TN178394805-83-1
    Isolicoflavonol 以可逆和混合的方式抑制人羧酸酯酶2介导的荧光素二乙酸酯水解, Ki 小于1.0 μM。
    • ¥ 6120
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  • Kazinol U
    TN43831238116-48-7
    Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-κB pathway in pancreatic β-cells reduces cell damage. Kazinol U shows estrogenic activity with ligand-activity of estrogen receptor, transcriptional activity of estrogen -responsive element-reporter genes, it may have beneficial effects in the treatment of menopausal symptoms.
    • ¥ 2310
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  • 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone
    TN30841353676-65-9
    5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone 具有抗癌活性,体外对 ER 阳性乳腺癌MCF-7细胞表现出较强的抗增殖作用,对MCF-7细胞的IC50值为4.41 uM。5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone 能显著下调雌激素受体-α (ER-α)的表达浓度,并能抑制人乳腺癌细胞系BCAP-37异种移植模型体内的肿瘤生长。
    • ¥ 12600
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  • Broussoflavonol F
    TMA0593162558-94-3
    Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase. Broussoflavonol F
    • ¥ 4800
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  • 2'-O-Methylbroussonin C
    TN2499376362-03-7
    2'-O-Methylbroussonin C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2499,CAS号为 376362-03-7。
    • ¥ 4280
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  • 7,3'-Dihydroxy-4'-methoxyflavan
    TN3211162290-05-3
    7,3'-Dihydroxy-4'-methoxyflavan是一种天然产物,属于桑科构树属,其产品编号为 TN3211,CAS号为 162290-05-3。7,3'-Dihydroxy-4'-methoxyflavan可用作对照参考。
    • ¥ 1960
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  • Dodonaflavonol
    TN38801392213-93-2
    Dodonaflavonol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3880,CAS号为 1392213-93-2。
    • ¥ 4510
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  • (2S)-7,4'-Dihydroxy-3'-prenylflavan
    TN3214376361-96-5
    7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity.
    • ¥ 2310
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  • 5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone
    TN30851605304-56-0
    5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone is a natural compound isolated from Broussonetia papyrifera.
    • ¥ 3940
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  • Kazinol A
    TN438299624-28-9
    Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M against XOD. Kazinol A may be a candidate for the development of effective anti-cancer drug on h
    • ¥ 2240
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  • Broussonin B
    TN565573731-86-9
    Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.B
    • ¥ 3090
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  • Broussonin A
    TN353973731-87-0
    Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. Broussonin A c
    • ¥ 3090
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  • Broussonin E
    TN354190902-21-9
    Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the treatment of inflammation-related
    • ¥ 5100
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  • Broussonetine A
    TN1452173220-07-0
    Broussonetines A-H are glycosidase inhibitors.
    • ¥ 2850
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  • Broussonin C
    TN354076045-49-3
    Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
    • ¥ 9600
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  • 4'-O-Demethylbroussonin A
    TN3053376361-97-6
    4'-O-Demethylbroussonin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3053,CAS号为 376361-97-6。
    • ¥ 9980
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  • 2'-O-Methylbroussonin A
    TN2788127757-13-5
    2'-O-Methylbroussonin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2788,CAS号为 127757-13-5。
    • ¥ 2760
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