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GSPT1 Protein, Human, Recombinant (His & Myc)

Synonyms: GSPT1, G1 to S phase transition protein 1 homolog, Eukaryotic peptide chain release factor subunit 3a, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ERF3A
货号 TMPH-01308 一键复制产品信息
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Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. GSPT1 Protein, Human, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 59.8 kDa and the accession number is P15170.

GSPT1 Protein, Human, Recombinant (His & Myc)

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货号 TMPH-01308

别名 GSPT1, G1 to S phase transition protein 1 homolog, Eukaryotic peptide chain release factor subunit 3a, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ERF3A

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. GSPT1 Protein, Human, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 59.8 kDa and the accession number is P15170.

GSPT1 Protein, Human, Recombinant (His & Myc)
规格价格库存数量
5 μg
¥ 783
现货
10 μg
¥ 1,290
现货
20 μg
¥ 2,170
现货
50 μg
¥ 3,220
20日内发货
100 μg
¥ 4,690
20日内发货
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颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. GSPT1 Protein, Human, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 59.8 kDa and the accession number is P15170.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
种属
Human
表达系统
P. pastoris (Yeast)
标签
N-10xHis, C-Myc
蛋白编号P15170
氨基酸序列
MELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
蛋白构建
1-499 aa
蛋白纯度
> 85% as determined by SDS-PAGE.
GSPT1 Protein, Human, Recombinant (His & Myc)
缓冲液
Tris-based buffer, 50% glycerol
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
GSPT1, G1 to S phase transition protein 1 homolog, Eukaryotic peptide chain release factor subunit 3a, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ERF3A
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量59.8 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

GSPT 1
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